[PDF][PDF] Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior

…, Y Salzberg, AH Chaubey, RA Bola, JR Hoffman… - Current biology, 2022 - cell.com
The effect of the detailed connectivity of a neural circuit on its function and the resulting behavior
of the organism is a key question in many neural systems. Here, we study the circuit for …

Sex-specific topology of the nociceptive circuit shapes dimorphic behavior in C. elegans

…, G Goldman, AH Chaubey, RA Bola, JR Hoffman… - Biorxiv, 2021 - biorxiv.org
How sexually dimorphic behavior is encoded in the nervous system is poorly understood.
Here, we characterize the dimorphic nociceptive behavior in C. elegans and study the …

Monoclonal antibody 2C6 targets a cross-clade conformational epitope in gp41 with highly active antibody-dependent cell cytotoxicity

…, M Garrett, MM van Haaren, J Hoffman… - Journal of …, 2019 - Am Soc Microbiol
Previous studies in our laboratory characterized a panel of highly mutated HIV-specific
conformational epitope-targeting antibodies (Abs) from a panel of HIV-infected long-term …

Clonal expansion and markers of directed mutation of IGHV4-34 B cells in plasmablasts during Kawasaki disease

AJ Chang, S Baron, J Hoffman, MD Hicar - Molecular immunology, 2022 - Elsevier
Kawasaki disease (KD) is the leading cause of acquired heart disease in children. The
cause remains unknown; however, epidemiologic and demographic data support a single …

[HTML][HTML] Highly mutated monoclonal antibody 3F2 targets a conformational and strain-restricted epitope in human immunodeficiency virus gp41 with significant …

D DeCotes, S Baron, J Hoffman, M Garrett, H Sojar… - Archives of …, 2022 - Springer
Identifying epitope targets by studying the native antibody (Ab) response can identify potential
novel vaccine constructs. Studies suggest that long-term non-progressor (LTNP) subjects …

Assessment of antibody interference of enfuvirtide (T20) function shows assay dependent variability

M Smith, J Hoffman, H Sojar, R Aalinkeel… - Current HIV …, 2018 - ingentaconnect.com
Background: During HIV infection, fusion of the viral and cellular membranes is dependent
on folding of the gp41 trimer into a six-helix bundle. Fusion inhibitors, such as the …

Neuromuscular plasticity during and following 3 wk of human forearm cast immobilization

…, JL Lane, LA Damron, RL Hoffman - Journal of Applied …, 2008 - journals.physiology.org
Prolonged reductions in muscle activity results in alterations in neuromuscular properties;
however, the time course of adaptations is not fully understood, and many of the specific …

Three weeks of caloric restriction alters protein metabolism in normal-weight, young men

…, MA Horning, GA Brooks, AR Hoffman… - American Journal …, 2005 - journals.physiology.org
The effects of prolonged caloric restriction (CR) on protein kinetics in lean subjects has not
been investigated previously. The purpose of this study was to test the hypotheses that 21 …

The BFG and the Spaghetti Book Club: A Case Study of Children as Critics

AR Hoffman - Children's Literature in Education, 2010 - Springer
Situated at the intersections of ethnography, childhood studies, literary studies, and education
research, this reception study seeks to access real children’s responses to a particular text…

Determining the Critical Dose Threshold of Electron-Induced Electron Yield for Minimally Charged Highly Insulating Materials

R Hoffman, J Abbott, JR Dennison - 2006 - digitalcommons.usu.edu
When incident energetic electrons interact with a material, they excite electrons within the
material to escape energies. The electron emission is quantified as the ratio of emitted …