Function and regulation of Dyrk1A: towards understanding Down syndrome
Down syndrome (DS) is associated with a variety of symptoms, such as incapacitating mental
retardation and neurodegeneration (ie, Alzheimer’s disease), that prevent patients from …
retardation and neurodegeneration (ie, Alzheimer’s disease), that prevent patients from …
[HTML][HTML] New perspectives of Dyrk1A role in neurogenesis and neuropathologic features of Down syndrome
Down syndrome (DS) is one of the most common genetic disorders accompanying with
mental retardation, cognitive impairment, and deficits in learning and memory. The brains with …
mental retardation, cognitive impairment, and deficits in learning and memory. The brains with …
Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1
The most common genetic disorder Down syndrome (DS) displays various developmental
defects including mental retardation, learning and memory deficit, the early onset of …
defects including mental retardation, learning and memory deficit, the early onset of …
[HTML][HTML] Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells
Down syndrome (DS) is associated with many neural defects, including reduced brain size
and impaired neuronal proliferation, highly contributing to the mental retardation. Those …
and impaired neuronal proliferation, highly contributing to the mental retardation. Those …
[PDF][PDF] CaMKII phosphorylation of TARPγ-8 is a mediator of LTP and learning and memory
Protein phosphorylation is an essential step for the expression of long-term potentiation (LTP),
a long-lasting, activity-dependent strengthening of synaptic transmission widely regarded …
a long-lasting, activity-dependent strengthening of synaptic transmission widely regarded …
[HTML][HTML] The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets
Lipid droplets (LDs) are crucial organelles for energy storage and lipid homeostasis.
Autophagy of LDs is an important pathway for their catabolism, but the molecular mechanisms …
Autophagy of LDs is an important pathway for their catabolism, but the molecular mechanisms …
Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome
Down syndrome (DS) is the most common genetic disorder, characterized by mental
retardation, congenital heart abnormalities, and susceptibility to Alzheimer's disease (AD). Brain …
retardation, congenital heart abnormalities, and susceptibility to Alzheimer's disease (AD). Brain …
Development of the stress response inventory
KB KOH, JK Park, CH KIM - Journal of Korean …, 2000 - pesquisa.bvsalud.org
OBJECTIVE: The purpose of this study was to develop the stress response inventory (SRI)
which includes emotional, somatic, cognitive, and behavioral stress responses, and then to …
which includes emotional, somatic, cognitive, and behavioral stress responses, and then to …
Development of the stress response inventory and its application in clinical practice
KB Koh, JK Park, CH Kim, S Cho - Psychosomatic medicine, 2001 - journals.lww.com
Objective The purpose of this study was to develop the Stress Response Inventory (SRI), which
includes emotional, somatic, cognitive, and behavioral stress responses, and then to use …
includes emotional, somatic, cognitive, and behavioral stress responses, and then to use …
Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP
J Park, JY Sung, J Park, WJ Song… - Journal of cell …, 2012 - journals.biologists.com
Neural Wiskott–Aldrich syndrome protein (N-WASP) is involved in tight regulation of actin
polymerization and dynamics. N-WASP activity is regulated by intramolecular interaction, …
polymerization and dynamics. N-WASP activity is regulated by intramolecular interaction, …