User profiles for Jordan D. Zehr
Jordan D ZehrPostdoctoral Associate, Cornell University Verified email at cornell.edu Cited by 53 |
Conserved recombination patterns across coronavirus subgenera
Recombination contributes to the genetic diversity found in coronaviruses and is known to
be a prominent mechanism whereby they evolve. It is apparent, both from controlled …
be a prominent mechanism whereby they evolve. It is apparent, both from controlled …
Evolutionary shortcuts via multinucleotide substitutions and their impact on natural selection analyses
Inference and interpretation of evolutionary processes, in particular of the types and targets
of natural selection affecting coding sequences, are critically influenced by the assumptions …
of natural selection affecting coding sequences, are critically influenced by the assumptions …
[HTML][HTML] Recent zoonotic spillover and tropism shift of a canine coronavirus is associated with relaxed selection and putative loss of function in NTD subdomain of …
A canine coronavirus (CCoV) has now been reported from two independent human
samples from Malaysia (respiratory, collected in 2017–2018; CCoV-HuPn-2018) and Haiti (urine, …
samples from Malaysia (respiratory, collected in 2017–2018; CCoV-HuPn-2018) and Haiti (urine, …
[PDF][PDF] Genomes of endangered great hammerhead and shortfin mako sharks reveal historic population declines and high levels of inbreeding in great hammerhead
Despite increasing threats of extinction to Elasmobranchii (sharks and rays), whole genome-based
conservation insights are lacking. Here, we present chromosome-level genome …
conservation insights are lacking. Here, we present chromosome-level genome …
Natural selection differences detected in key protein domains between non-pathogenic and pathogenic feline coronavirus phenotypes
Feline coronaviruses (FCoVs) commonly cause mild enteric infections in felines worldwide (termed
feline enteric coronavirus [FECV]), with around 12 per cent developing into deadly …
feline enteric coronavirus [FECV]), with around 12 per cent developing into deadly …
[HTML][HTML] Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution
Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of
life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, …
life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, …
[HTML][HTML] RASCL: Rapid Assessment of Selection in CLades through molecular sequence analysis
An important unmet need revealed by the COVID-19 pandemic is the near-real-time identification
of potentially fitness-altering mutations within rapidly growing SARS-CoV-2 lineages. …
of potentially fitness-altering mutations within rapidly growing SARS-CoV-2 lineages. …
[HTML][HTML] RASCL: rapid assessment of SARS-CoV-2 clades through molecular sequence analysis
An important component of efforts to manage the ongoing COVID19 pandemic is the R apid
A ssessment of how natural selection contributes to the emergence and proliferation of …
A ssessment of how natural selection contributes to the emergence and proliferation of …
Human HspB1, HspB3, HspB5 and HspB8
Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of
life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, …
life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, …
[HTML][HTML] Fast and accurate genome-wide predictions and structural modeling of protein–protein interactions using Galaxy
Background Protein–protein interactions play a crucial role in almost all cellular processes.
Identifying interacting proteins reveals insight into living organisms and yields novel drug …
Identifying interacting proteins reveals insight into living organisms and yields novel drug …