User profiles for Jordan D. Zehr

Jordan D Zehr

Postdoctoral Associate, Cornell University
Verified email at cornell.edu
Cited by 53

Conserved recombination patterns across coronavirus subgenera

…, D Robertson, SL Kosakovsky Pond, JD Zehr… - Virus …, 2022 - academic.oup.com
Recombination contributes to the genetic diversity found in coronaviruses and is known to
be a prominent mechanism whereby they evolve. It is apparent, both from controlled …

Evolutionary shortcuts via multinucleotide substitutions and their impact on natural selection analyses

AG Lucaci, JD Zehr, D Enard… - Molecular Biology …, 2023 - academic.oup.com
Inference and interpretation of evolutionary processes, in particular of the types and targets
of natural selection affecting coding sequences, are critically influenced by the assumptions …

[HTML][HTML] Recent zoonotic spillover and tropism shift of a canine coronavirus is associated with relaxed selection and putative loss of function in NTD subdomain of …

JD Zehr, SLK Pond, DP Martin, K Ceres, GR Whittaker… - Viruses, 2022 - mdpi.com
A canine coronavirus (CCoV) has now been reported from two independent human
samples from Malaysia (respiratory, collected in 2017–2018; CCoV-HuPn-2018) and Haiti (urine, …

[PDF][PDF] Genomes of endangered great hammerhead and shortfin mako sharks reveal historic population declines and high levels of inbreeding in great hammerhead

MJ Stanhope, KM Ceres, Q Sun, M Wang, JD Zehr… - Iscience, 2023 - cell.com
Despite increasing threats of extinction to Elasmobranchii (sharks and rays), whole genome-based
conservation insights are lacking. Here, we present chromosome-level genome …

Natural selection differences detected in key protein domains between non-pathogenic and pathogenic feline coronavirus phenotypes

JD Zehr, SL Kosakovsky Pond, JK Millet… - Virus …, 2023 - academic.oup.com
Feline coronaviruses (FCoVs) commonly cause mild enteric infections in felines worldwide (termed
feline enteric coronavirus [FECV]), with around 12 per cent developing into deadly …

[HTML][HTML] Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution

R Benndorf, R Velazquez, JD Zehr, SLK Pond… - Cell Stress and …, 2022 - Springer
Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of
life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, …

[HTML][HTML] RASCL: Rapid Assessment of Selection in CLades through molecular sequence analysis

AG Lucaci, JD Zehr, SD Shank, D Bouvier, A Ostrovsky… - Plos one, 2022 - journals.plos.org
An important unmet need revealed by the COVID-19 pandemic is the near-real-time identification
of potentially fitness-altering mutations within rapidly growing SARS-CoV-2 lineages. …

[HTML][HTML] RASCL: rapid assessment of SARS-CoV-2 clades through molecular sequence analysis

AG Lucaci, JD Zehr, SD Shank, D Bouvier, H Mei… - BioRxiv, 2022 - ncbi.nlm.nih.gov
An important component of efforts to manage the ongoing COVID19 pandemic is the R apid
A ssessment of how natural selection contributes to the emergence and proliferation of …

Human HspB1, HspB3, HspB5 and HspB8

R Benndorf, R Velazquez, JD Zehr, SLK Pond… - Cell Stress & …, 2022 - JSTOR
Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of
life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, …

[HTML][HTML] Fast and accurate genome-wide predictions and structural modeling of protein–protein interactions using Galaxy

…, D Bouvier, N Coraor, SD Shank, JD Zehr… - BMC …, 2023 - Springer
Background Protein–protein interactions play a crucial role in almost all cellular processes.
Identifying interacting proteins reveals insight into living organisms and yields novel drug …