User profiles for Jordan Sicherman
Jordan Sicherman10x Genomics Verified email at 10xgenomics.com Cited by 56 |
[HTML][HTML] High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis
…, CA Morrison, MF Oliveira, JT Sicherman… - Nature …, 2023 - nature.com
Single-cell and spatial technologies that profile gene expression across a whole tissue are
revolutionizing the resolution of molecular states in clinical samples. Current commercially …
revolutionizing the resolution of molecular states in clinical samples. Current commercially …
[HTML][HTML] Deconvolution of clinical variance in CAR-T cell pharmacology and response
Chimeric antigen receptor T cell (CAR-T) expansion and persistence vary widely among
patients and predict both efficacy and toxicity. However, the mechanisms underlying clinical …
patients and predict both efficacy and toxicity. However, the mechanisms underlying clinical …
Curation of over 10 000 transcriptomic studies to enable data reuse
Vast amounts of transcriptomic data reside in public repositories, but effective reuse remains
challenging. Issues include unstructured dataset metadata, inconsistent data processing …
challenging. Issues include unstructured dataset metadata, inconsistent data processing …
[HTML][HTML] Estimating and correcting for off-target cellular contamination in brain cell type specific RNA-seq data
J Sicherman, DF Newton, P Pavlidis… - Frontiers in molecular …, 2021 - frontiersin.org
Transcriptionally profiling minor cellular populations remains an ongoing challenge in molecular
genomics. Single-cell RNA sequencing has provided valuable insights into a number of …
genomics. Single-cell RNA sequencing has provided valuable insights into a number of …
Author Correction: Deconvolution of clinical variance in CAR-T cell pharmacology and response
…, C Zmurchok, A Deyati, J Sicherman… - nature …, 2023 - ncbi.nlm.nih.gov
In the version of this article initially published, there were conversion errors in the display
equations presented in the “Model structure and assumptions” section of the Methods and the “…
equations presented in the “Model structure and assumptions” section of the Methods and the “…
Cataloging the potential functional diversity of Cacna1e splice variants using long-read sequencing
Voltage gated calcium channels (VGCCs) regulate the influx of calcium ions in many cell
types, but our lack of knowledge about the plethora of VGCC splice variants remains a gap in …
types, but our lack of knowledge about the plethora of VGCC splice variants remains a gap in …
Large-scale mining of differential expression data for insight into gene function
J Sicherman - 2021 - open.library.ubc.ca
… submitted by Jordan Sicherman … Besides raw data acquisition, all analysis presented in
this work was done by me (Jordan Sicherman), including the development of the web interface. …
this work was done by me (Jordan Sicherman), including the development of the web interface. …
92 Characterization of the tumor microenvironment using the xenium in situ platform and FFPE tissue array technology
…, S Mohabbat, R Gantt, F Wagner, J Sicherman… - 2023 - jitc.bmj.com
Background Tissue array technology enables screening of multiple tissue samples on a
single microscopic slide and is an assistive tool in the field of oncology, given its ability to …
single microscopic slide and is an assistive tool in the field of oncology, given its ability to …
Corrections & amendments
In the version of this article initially published, there were conversion errors in the display
equations presented in the “Model structure and assumptions” section of the Methods and the “…
equations presented in the “Model structure and assumptions” section of the Methods and the “…
Prioritizing genes with functionally distinct splice isoforms
SA Bhuiyan - 2020 - open.library.ubc.ca
… Jordan Sicherman built the IsoVision tool I use for visualization. Jose Rafael Dimayacyac
performed comparisons … Jordan Sicherman built the IsoVision tool I use for visualization. …
performed comparisons … Jordan Sicherman built the IsoVision tool I use for visualization. …