The blood–brain barrier (BBB), a critical guardian of communication between the periphery
and the brain, is frequently compromised in neurological diseases such as multiple sclerosis (…

We generated a transgenic mouse model expressing the apical hypertrophic
cardiomyopathy-causing mutation ACTC E99K at 50% of total heart actin and compared it with actin …

Rationale Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine are increasingly
used for the treatment of depression in children. Limited data are, however, available on …

Repetitive overload is a primary factor in tendon injury, causing progressive accumulation of
matrix damage concurrent with a cellular response. However, it remains unclear how these …

Uncontrolled microglial response is core to neuroinflammatory brain diseases. The correlation
between the mitochondrial protein TSPO and inflammation has so far failed to explain …

Background In captive colonies, owl monkeys’ mothers sometimes reject their newborns. To
prevent, mortality infants are manually raised by veterinarians. Both parental separation and …

1. SUMMARY Background The mothers of owl monkeys sometimes reject their new-borns.
When this occurs in captive colonies, the rejected infants are manually raised by veterinarians…

It has been suggested that preculturing immature oocytes in a manner that maintains them
in meiotic arrest may improve cytoplasmic maturation and, thereby, the eventual …

A new, interactive framework supports the evaluation of in vivo and ex vivo research proposals
from a sex inclusive research perspective delivering a traffic light classification, indicating …

The use of animal in biomedical research remains a critical compromise. Research and
higher education institutions play a major role in educating on the use of animal and such …