Immune checkpoint inhibitors have been successful across several tumor types; however,
their efficacy has been uncommon and unpredictable in glioblastomas (GBM), where <10% of …

Glioblastomas (GBMs) diffusely infiltrate the brain, making complete removal by surgical
resection impossible. The mixture of neoplastic and nonneoplastic cells that remain after …

Background Despite extensive molecular characterization, we lack a comprehensive
understanding of lineage identity, differentiation, and proliferation in high-grade gliomas (HGGs). …

OBJECTIVE Extent of resection is an important prognostic factor in patients undergoing
surgery for glioblastoma (GBM). Recent evidence suggests that intravenously administered …

Objective Somatic variants are a recognized cause of epilepsy‐associated focal malformations
of cortical development (MCD). We hypothesized that somatic variants may underlie a …

Although immune signaling has emerged as a defining feature of the glioma microenvironment,
how the underlying structure of the glioma-infiltrating T-cell population differs from that of …

BACKGROUND Accurate tissue sampling in nonenhancing (NE) gliomas is a unique surgical
challenge due to their intratumoral histological heterogeneity and absence of contrast …

Objective Subependymomas are infrequent, low-grade gliomas associated with the ventricular
system and the spinal cord. Little is known about the origin and natural history of these …

Author Correction: Immune and genomic correlates of response to anti-PD-1 immunotherapy
in glioblastoma. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …

Background Gliomas comprise the most common type of primary brain tumor, are highly
invasive, and often fatal. IDH-mutated gliomas are particularly challenging to image and there is …