During the past decade, possible advancement in timing of puberty has been reported in
the United States. In addition, early pubertal development and an increased incidence of …

… Jorma Toppari, Departments of Pediatrics and Physiology, University of Turku, Finland, …
The final manuscript was edited by Jorma Toppari together with Niels E. Skakkebak and …

The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to the
scientific community about how environmental endocrine-disrupting chemicals (EDCs) affect …

The development of the microbiome from infancy to childhood is dependent on a range of
factors, with microbial–immune crosstalk during this time thought to be involved in the …

Aims/hypothesis Islet autoantibodies, in addition to elevated blood glucose, define type 1
diabetes. These autoantibodies are detectable for a variable period of time before diabetes …

It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level (…

This Executive Summary to the Endocrine Society's second Scientific Statement on environmental
endocrine-disrupting chemicals (EDCs) provides a synthesis of the key points of the …

Phthalates adversely affect the male reproductive system in animals. We investigated
whether phthalate monoester contamination of human breast milk had any influence on the …

Type 1 diabetes (T1D) is an autoimmune disease that targets pancreatic islet beta cells and
incorporates genetic and environmental factors 1 , including complex genetic elements 2 , …

Recent reports have indicated a decrease in semen quality of men in some countries, and
suggested regional differences. A study was undertaken of semen samples from 1082 fertile …