During the past decade, catheter ablation of atrial fibrillation (AF) has evolved rapidly from an
investigational procedure to its current status as a commonly performed ablation procedure …

EXCITABLE media can support spiral waves rotating around an organizing centre 1–7 . Spiral
waves have been discovered in different types of autocatalytic chemical reactions 8,9 and …

Cardiac fibrillation (spontaneous, asynchronous contractions of cardiac muscle fibres) is the
leading cause of death in the industrialized world 1 , yet it is not clear how it occurs. It has …

Background— The identification of sites of dominant activation frequency during atrial fibrillation
(AF) in humans and the effect of ablation at these sites have not been reported. Methods …

Background—Atrial fibrillation (AF) has traditionally been described as aperiodic or random.
Yet, ongoing sources of high-frequency periodic activity have recently been suggested to …

Short QT syndrome (SQTS) leads to an abbreviated QTc interval and predisposes patients
to life-threatening arrhythmias. To date, two forms of the disease have been identified: SQT1, …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and the major
cardiac cause of stroke. Recent studies in patients with paroxysmal AF have shown that the …

Background—The activation patterns that underlie the irregular electrical activity during
atrial fibrillation (AF) have traditionally been described as disorganized or random. Recent …

Many mechanisms have been proposed to explain ventricular fibrillation, which is the
precursor to sudden cardiac death, the leading cause ofdeath in the industrialized world (1). A …

The National Heart, Lung, and Blood Institute convened an expert panel April 28 to 29, 2008,
to identify gaps and recommend research strategies to prevent atrial fibrillation (AF). The …