… This study is dedicated to the memory of our friend and colleague, José Luis Gómez-Skarmeta.
Chinese muntjac cells were kindly provided by WR Brinkley. Skin fibroblasts of Indian …

In Drosophila imaginal wing discs, the achaete–scute (ac–sc) proneural genes and rhomboid
(veinlet) are expressed in highly resolved patterns that prefigure the positions of sensory …

Recent studies of the genome architecture of vertebrates have uncovered two unforeseen
aspects of its organization. First, large regions of the genome, called gene deserts, are devoid …

Type 2 diabetes affects over 300 million people, causing severe complications and premature
death, yet the underlying molecular mechanisms are largely unknown. Pancreatic islet …

The unicellular ancestor of animals had a complex repertoire of genes linked to multicellular
processes. This suggests that changes in the regulatory genome, rather than in gene …

Heterozygous mutations in p63 are associated with split hand/foot malformations (SHFM),
orofacial clefting, and ectodermal abnormalities. Elucidation of the p63 gene network that …

The generation of distinctive cell types that form different tissues and organs requires
precise, temporal and spatial control of gene expression. This depends on specific cis-regulatory …

The Iroquois (Iro) family of genes are found in nematodes, insects and vertebrates. They
usually occur in one or two genomic clusters of three genes each and encode transcriptional …

Genome-wide association studies (GWAS) have reproducibly associated variants within
introns of FTO with increased risk for obesity and type 2 diabetes (T2D) 1 , 2 , 3 . Although the …

There is no obvious morphological counterpart of the autopod (wrist/ankle and digits) in
living fishes. Comparative molecular data may provide insight into understanding both the …