Low miR-218 expression in the medial prefrontal cortex (mPFC) is a consistent trait of
depression. Here we assessed whether miR-218 in the mPFC confers resilience or susceptibility …

Initiating drug use during adolescence increases the risk of developing addiction or other
psychopathologies later in life, with long-term outcomes varying according to sex and exact …

The prefrontal cortex (PFC) is divided into subregions, including the medial and orbital prefrontal
cortices. Dopamine connectivity in the medial PFC (mPFC) continues to be established …

Inhibitory control deficits are prevalent in multiple neuropsychiatric conditions. The
communication- as well as the connectivity- between corticolimbic regions of the brain are …

The guidance cue receptor DCC controls mesocortical dopamine development in adolescence.
Repeated exposure to an amphetamine regimen of 4 mg/kg during early adolescence …

The development of the dopamine input to the medial prefrontal cortex occurs during
adolescence and is a process that is vulnerable to disruption by stimulant drugs such as …

The possibility of establishing a metric of individual genetic risk for a particular disease or
trait has sparked the interest of the clinical and research communities, with many groups …

Initiating drug use during adolescence increases the risk of developing addiction and
psychiatric disorders later in life, with long-term outcomes varying according to sex and exact …

Initiation of drug use in adolescence is a strong predictor of the incidence and severity of
addiction throughout life. Adolescence is a period of dynamic refinement in the organization of …

Background: Cannabis is one of the most frequently used substances by adolescents. Early
exposure to psychoactive compounds has been shown to alter normal brain development …