User profiles for Jose Guevara-Coto

Jose Guevara-Coto

IncellDx
Verified email at incelldx.com
Cited by 543

[HTML][HTML] Immune-based prediction of COVID-19 severity and chronicity decoded using machine learning

BK Patterson, J Guevara-Coto, R Yogendra… - Frontiers in …, 2021 - frontiersin.org
Expression of CCR5 and its cognate ligands have been implicated in COVID-19 pathogenesis,
consequently therapeutics directed against CCR5 are being investigated. Here, we …

[HTML][HTML] Multistability in macrophage activation pathways and metabolic implications

C Geiß, E Salas, J Guevara-Coto, A Régnier-Vigouroux… - Cells, 2022 - mdpi.com
Macrophages are innate immune cells with a dynamic range of reversible activation states
including the classical pro-inflammatory (M1) and alternative anti-inflammatory (M2) states. …

Evaluating hyper-parameter tuning using random search in support vector machines for software effort estimation

…, C Quesada-López, J Guevara-Coto… - Proceedings of the 16th …, 2020 - dl.acm.org
Studies in software effort estimation (SEE) have explored the use of hyper-parameter tuning
for machine learning algorithms (MLA) to improve the accuracy of effort estimates. In other …

[HTML][HTML] SARS-CoV-2 S1 protein persistence in SARS-CoV-2 negative post-vaccination individuals with long COVID/PASC-like symptoms

…, J Bream, M Kreimer, RV Heide, J Guevara-Coto… - 2022 - europepmc.org
Background: We sought to determine the immunologic abnormalities in patients following
SARS-CoV-2 vaccines who experience post-acute sequelae of COVID-19 (PASC)-like …

[HTML][HTML] Case series: maraviroc and pravastatin as a therapeutic option to treat long COVID/Post-acute sequelae of COVID (PASC)

BK Patterson, R Yogendra, J Guevara-Coto… - Frontiers in …, 2023 - frontiersin.org
Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication of
SARS-CoV-2 infection that continues to debilitate millions worldwide thus highlighting the public …

[PDF][PDF] MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer

…, G Vásquez-Vargas, Y Oses-Vargas, J Guevara-Coto… - IScience, 2021 - cell.com
We hypothesize that dosage compensation of critical genes arises from systems-level
properties for cancer cells to withstand the negative effects of aneuploidy. We identified several …

Bemisia tabaci Biotype Q is present in Costa Rica

JA Guevara-Coto, N Barboza-Vargas… - European Journal of …, 2011 - Springer
Whiteflies are an insect group that comprises multiple species and biotypes, capable of
affecting crops by phloem feeding, virus transmission and promotion of fungal colonization. The …

[HTML][HTML] Protein sector analysis for the clustering of disease-associated mutations

J Guevara-Coto, CE Schwartz, L Wang - BMC genomics, 2014 - Springer
Background The importance of mutations in disease phenotype has been studied, with
information available in databases such as OMIM. However, it remains a research challenge for …

[HTML][HTML] Cytokine Hub Classification of PASC, ME-CFS and other PASC-like Conditions

BK Patterson, J Guevara-Coto, EB Francisco… - 2022 - europepmc.org
Background: Post-acute sequelae of COVID-19 (PASC) is a growing healthcare and economic
concern affecting as many as 10%-30% of those infected with COVID-19. Though the …

Classifying and understanding tor traffic using tree-based models

P Calvo, J Guevara-Coto, A Lara - 2020 IEEE Latin-American …, 2020 - ieeexplore.ieee.org
Over the past years the use of anonymization services has gained significant relevance as
more users are interested in protecting their data and privacy on the internet. One of the most …