Common variants at 5q22 associate with pediatric eosinophilic esophagitis

ME Rothenberg, JM Spergel, JD Sherrill, K Annaiah… - Nature …, 2010 - nature.com
Eosinophilic esophagitis (EoE) is an allergic disorder characterized by the accumulation of
eosinophils in the esophagus. We report association of EoE with variants at chromosome …

Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease

LC Kottyan, BP Davis, JD Sherrill, K Liu, M Rochman… - Nature …, 2014 - nature.com
Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder associated with allergic
hypersensitivity to food. We interrogated >1.5 million genetic variants in EoE cases of …

Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis

JD Sherrill, PS Gao, EM Stucke, C Blanchard… - Journal of Allergy and …, 2010 - Elsevier
… Author links open overlay panel Joseph D. Sherrill PhD a , Pei-Song Gao MD, PhD b ,
Emily M. Stucke BA a , Carine Blanchard PhD a , Margaret H. Collins MD c , Phil E. …

MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers

TX Lu, JD Sherrill, T Wen, AJ Plassard, JA Besse… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: The role of microRNAs (miRNAs), a key class of regulators of mRNA expression
and translation, in patients with eosinophilic esophagitis (EoE) has not been explored. …

Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing

JD Sherrill, K Kc, C Blanchard, EM Stucke… - Genes & …, 2014 - nature.com
Eosinophilic esophagitis (EoE) is an allergic inflammatory disorder of the esophagus that is
compounded by genetic predisposition and hypersensitivity to environmental antigens. …

Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies

JD Sherrill, ME Rothenberg - Journal of Allergy and Clinical Immunology, 2011 - Elsevier
Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus that is
compounded by both genetic predisposition and aberrant responses to environmental …

Population-level rhythms in human skin with implications for circadian medicine

…, JJ Hughey, R Tasseff, JD Sherrill… - Proceedings of the …, 2018 - National Acad Sciences
Skin is the largest organ in the body and serves important barrier, regulatory, and sensory
functions. The epidermal layer shows rhythmic physiological responses to daily environmental …

Phenotypic characterization of eosinophilic esophagitis in a large multicenter patient population from the consortium for food allergy research

…, SH Sicherer, JP Abonia, JD Sherrill… - The Journal of Allergy …, 2018 - Elsevier
… Wood MD d , Donald YM Leung MD, PhD e , Glenn T. Furuta MD f , David M. Fleischer
MD f … Pablo Abonia MD h , Joseph D. Sherrill PhD h , Hugh A. Sampson MD a , Marc E. …

Profound loss of esophageal tissue differentiation in patients with eosinophilic esophagitis

…, NP Azouz, JM Caldwell, KC Kiran, JD Sherrill… - Journal of allergy and …, 2017 - Elsevier
Background A key question in the allergy field is to understand how tissue-specific disease
is manifested. Eosinophilic esophagitis (EoE) is an emerging tissue-specific allergic disease …

[HTML][HTML] A population-based gene expression signature of molecular clock phase from a single epidermal sample

G Wu, MD Ruben, LJ Francey, DF Smith, JD Sherrill… - Genome medicine, 2020 - Springer
Background For circadian medicine to influence health, such as when to take a drug or
undergo a procedure, a biomarker of molecular clock phase is required––one that is easily …