User profiles for Joseph E Knox
Joseph KnoxApplied Mathematics, University of Washington Verified email at uw.edu Cited by 783 |
Hierarchical organization of cortical and thalamic connectivity
The mammalian cortex is a laminar structure containing many areas and cell types that are
densely interconnected in complex ways, and for which generalizable principles of …
densely interconnected in complex ways, and for which generalizable principles of …
[PDF][PDF] Regional, layer, and cell-type-specific connectivity of the mouse default mode network
…, PA Groblewski, N Graddis, L Kuan, JE Knox… - Neuron, 2021 - cell.com
The evolutionarily conserved default mode network (DMN) is a distributed set of brain regions
coactivated during resting states that is vulnerable to brain disorders. How disease affects …
coactivated during resting states that is vulnerable to brain disorders. How disease affects …
Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease
A variety of Alzheimer's disease (AD) mouse models overexpress mutant forms of human
amyloid precursor protein (APP), producing high levels of amyloid β (Aβ) and forming plaques. …
amyloid precursor protein (APP), producing high levels of amyloid β (Aβ) and forming plaques. …
High-resolution data-driven model of the mouse connectome
Abstract Knowledge of mesoscopic brain connectivity is important for understanding inter-
and intraregion information processing. Models of structural connectivity are typically …
and intraregion information processing. Models of structural connectivity are typically …
The organization of intracortical connections by layer and cell class in the mouse brain
The mammalian cortex is a laminar structure composed of many cell types densely interconnected
in complex ways. Recent systematic efforts to map the mouse mesoscale connectome …
in complex ways. Recent systematic efforts to map the mouse mesoscale connectome …
[HTML][HTML] Endogenous pathology in tauopathy mice progresses via brain networks
Neurodegenerative tauopathies are hypothesized to propagate via brain networks. This is
uncertain because we have lacked precise network resolution of pathology. We therefore …
uncertain because we have lacked precise network resolution of pathology. We therefore …
High-Angle Backscatter from Snow on the Ground
JE Knox - Optical Engineering for Cold Environments, 1983 - spiedigitallibrary.org
In January and February of 1981 and 1982, the Ballistic Research Laboratory (BRL)
participated in SNOW-ONE at Camp Ethan Allen, VT, sponsored by the US Army Cold Regions …
participated in SNOW-ONE at Camp Ethan Allen, VT, sponsored by the US Army Cold Regions …
Brain X chromosome inactivation is not random and can protect from paternally inherited neurodevelopmental disease
Non-random (skewed) X chromosome inactivation (XCI) in the female brain can ameliorate
X-linked phenotypes, though clinical studies typically consider 80-90% skewing favoring the …
X-linked phenotypes, though clinical studies typically consider 80-90% skewing favoring the …
Behavioral Circuit-Specific Effects of Brain X-Chromosome Inactivation Determines X-Linked Phenotypic Penetrance
The precise anatomical degree of brain X chromosome inactivation (XCI) skewing that is
sufficient to drive X-linked neurodevelopmental disorders in females is not known. Here we …
sufficient to drive X-linked neurodevelopmental disorders in females is not known. Here we …
A brain network basis of Fragile X syndrome behavioral penetrance determined by X chromosome inactivation in female mice
X-chromosome inactivation (XCI) in females is vital for normal brain function and cognition,
as many X-linked genetic mutations lead to mental retardation and autism spectrum disorders…
as many X-linked genetic mutations lead to mental retardation and autism spectrum disorders…