Characterization of a novel coronavirus associated with severe acute respiratory syndrome

…, M Chen, S Tong, A Tamin, L Lowe, M Frace, JL DeRisi… - science, 2003 - science.org
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases
of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of …

Exploring the metabolic and genetic control of gene expression on a genomic scale

JL DeRisi, VR Iyer, PO Brown - Science, 1997 - science.org
DNA microarrays containing virtually every gene ofSaccharomyces cerevisiae were used to
carry out a comprehensive investigation of the temporal program of gene expression …

Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier

PA Takizawa, JL DeRisi, JE Wilhelm, RD Vale - Science, 2000 - science.org
Asymmetric localization of proteins plays a key role in many cellular processes, including cell
polarity and cell fate determination. Using DNA microarray analysis, we identified a plasma …

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM

…, BM Ueberheide, BT Aftab, MS Anderson, JL DeRisi… - Nature, 2022 - nature.com
Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive
lymphocytes attack the myelin sheath of the central nervous system. B lymphocytes in the …

[HTML][HTML] The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum

…, M Llinás, BL Pulliam, ED Wong, J Zhu, JL DeRisi - PLoS …, 2003 - journals.plos.org
Plasmodium falciparum is the causative agent of the most burdensome form of human
malaria, affecting 200–300 million individuals per year worldwide. The recently sequenced …

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

…, J Ihmels, DK Breslow, M Noble, JL DeRisi… - Nature, 2006 - nature.com
A major goal of biology is to provide a quantitative description of cellular behaviour. This task,
however, has been hampered by the difficulty in measuring protein abundances and their …

[PDF][PDF] Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy

…, AS Puschnik, M Phelps, A Kistler, JL DeRisi… - Cell, 2021 - cell.com
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an
ongoing global pandemic due in part to the challenge of identifying symptomatic, asymptomatic, …

Microarray-based detection and genotyping of viral pathogens

…, HA Boushey, D Ganem, JL DeRisi - Proceedings of the …, 2002 - National Acad Sciences
The detection of viral pathogens is of critical importance in biology, medicine, and agriculture.
Unfortunately, existing techniques to screen for a broad spectrum of viruses suffer from …

Yeast microarrays for genome wide parallel genetic and gene expression analysis

DA Lashkari, JL DeRisi, JH McCusker… - Proceedings of the …, 1997 - National Acad Sciences
We have developed high-density DNA microarrays of yeast ORFs. These microarrays can
monitor hybridization to ORFs for applications such as quantitative differential gene …

[HTML][HTML] Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris: The Tabula Muris Consortium

…, F Zhang, L Zhou, P Castro, D Croote, JL DeRisi… - Nature, 2018 - ncbi.nlm.nih.gov
We have created a compendium of single cell transcriptomic data from the model organism
Mus musculus comprising more than 100,000 cells from 20 organs and tissues. These data …