In the past decade, leptospirosis has emerged as a globally important infectious disease. It
occurs in urban environments of industrialised and developing countries, as well as in rural …

On 16 June, investigators on the covid-19 RECOVERY trial revealed in a press release 1 that
participants with severe covid-19 (2104) given 6 mg dexamethasone once daily had an 8-…

Background: Surprisingly, many inner-city residents have antibodies to Leptospira interrogans.
The manner in which these persons acquire this organism in the absence of recognized …

Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Background Although previous data indicate that the overall incidence of human leptospirosis
in the Peruvian Amazon is similar in urban and rural sites, severe leptospirosis has been …

Background. Pulmonary involvement in leptospirosis remains poorly recognized in regions
where it is endemic, despite reports of recent outbreaks and epidemic disease. Methods. A …

Human infection by leptospires has highly variable clinical manifestations, which range from
subclinical infection to fulminant disease. We conducted a population-based, cross-…

As part of a prospective study of leptospirosis and biodiversity of Leptospira in the Peruvian
Amazon, a new Leptospira species was isolated from humans with acute febrile illness. Field …

Background Renal carriage and shedding of leptospires is characteristic of carrier or
maintenance animal hosts. Sporadic reports indicate that after infection, humans may excrete …

Plasmodium vivax is a major public health burden, responsible for the majority of malaria
infections outside Africa. We explored the impact of demographic history and selective …