The identification of cancer-associated long noncoding RNAs (lncRNAs) and the investigation
of their molecular and biological functions are important to understand the molecular …

The immediate molecular mechanisms behind invasive melanoma are poorly understood.
Recent studies implicate microRNAs (miRNAs) as important agents in melanoma and other …

Expression of the long noncoding RNA (lncRNA) SPRY4-IT1 is low in normal human
melanocytes but high in melanoma cells. siRNA knockdown of SPRY4-IT1 blocks melanoma cell …

In this study, several formulations of nanoceria and dextran-nanoceria with curcumin, each
demonstrated to have anti-cancer properties, were synthesized and applied as treatment for …

Two‐partner secretion (TPS) is the most widely distributed secretion pathway known. These
systems export large exoproteins through highly conserved channel‐forming β‐barrel …

To identify epigenetically regulated miRNAs in melanoma, we treated a stage 3 melanoma
cell line WM1552C, with 5AzadC and/or 4-PBA. Several hypermethylated miRNAs were …

Prostate cancer is one of the leading causes of mortality among US males. There is an urgent
unmet need to develop sensitive and specific biomarkers for the early detection of prostate …

MicroRNA 211 (miR-211) negatively regulates genes that drive invasion of metastatic melanoma.
Compared to normal human melanocytes, miR-211 expression is significantly reduced …

Invasive melanoma is the most lethal form of skin cancer. The treatment of melanoma-derived
cell lines with 5-aza-2′-deoxycytidine (5-Aza-dC) markedly increases the expression of …

Two-partner secretion (TPS) systems, which export large proteins to the surface and/or
extracellular milieu of Gram-negative bacteria, are members of a large superfamily of protein …