[HTML][HTML] Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty

…, A Adiga, B Lewis, B Klahn, J Outten… - Nature …, 2023 - nature.com
Our ability to forecast epidemics far into the future is constrained by the many complexities
of disease systems. Realistic longer-term projections may, however, be possible under well-…

[HTML][HTML] Impact of SARS-CoV-2 vaccination of children ages 5–11 years on COVID-19 disease burden and resilience to new variants in the United States, November …

…, A Adiga, B Lewis, B Klahn, J Outten… - The Lancet Regional …, 2023 - thelancet.com
Background The COVID-19 Scenario Modeling Hub convened nine modeling teams to project
the impact of expanding SARS-CoV-2 vaccination to children aged 5–11 years on COVID-…

Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource

…, J Murga-Moreno, M Paris, J Outten… - Molecular biology …, 2021 - academic.oup.com
Drosophila melanogaster is a leading model in population genetics and genomics, and a
growing number of whole-genome data sets from natural populations of this species have …

[HTML][HTML] Informing pandemic response in the face of uncertainty. An evaluation of the US COVID-19 Scenario Modeling Hub

…, A Adiga, B Lewis, B Klahn, J Outten… - medRxiv, 2023 - ncbi.nlm.nih.gov
Our ability to forecast epidemics more than a few weeks into the future is constrained by the
complexity of disease systems, our limited ability to measure the current state of an epidemic…

Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering …

…, A Adiga, B Lewis, B Klahn, J Outten… - Elife, 2022 - elifesciences.org
In Spring 2021, the highly transmissible SARS-CoV-2 Delta variant began to cause increases
in cases, hospitalizations, and deaths in parts of the United States. At the time, with slowed …

[HTML][HTML] Potential impact of annual vaccination with reformulated COVID-19 vaccines: lessons from the US COVID-19 Scenario Modeling Hub

…, A Adiga, B Hurt, B Klahn, J Outten… - PLoS …, 2024 - journals.plos.org
Background Coronavirus Disease 2019 (COVID-19) continues to cause significant
hospitalizations and deaths in the United States. Its continued burden and the impact of annually …

Data-driven scalable pipeline using national agent-based models for real-time pandemic response and decision support

…, B Klahn, A Adiga, B Hurt, J Outten… - … Journal of High …, 2023 - journals.sagepub.com
This paper describes an integrated, data-driven operational pipeline based on national
agent-based models to support federal and state-level pandemic planning and response. The …

Ai-driven agent-based models to study the role of vaccine acceptance in controlling covid-19 spread in the us

…, P Porebski, B Klahn, J Outten… - … Conference on Big …, 2021 - ieeexplore.ieee.org
We study the role of vaccine acceptance in controlling the spread of COVID-19 in the US using
AI-driven agent-based models. Our study uses a 288 million node social contact network …

[HTML][HTML] Methods and developments in graphical pangenomics

J Outten, A Warren - Journal of the Indian Institute of Science, 2021 - Springer
Pangenomes are organized collections of the genomic information from related individuals
or groups. Graphical pangenomics is the study of these pangenomes using graphical …

Potential impact of annual vaccination with reformulated COVID-19 vaccines: lessons from the US COVID-19 Scenario Modeling Hub (preprint)

…, A Wilson, S Hoops, P Bhattacharya, D Machi, J Outten… - 2023 - pesquisa.bvsalud.org
… Sung-mok Jung; Sara L Loo; Emily Howerton; Lucie Contamin; Claire P Smith; Erica C
Carcelén; Katie Yan; Samantha J Bents; Jessi Espino; John Levander; Joseph C Lemaitre; …