Musicologists and linguists have often suggested that the prosody of a culture's spoken
language can influence the structure of its instrumental music. However, empirical data …

Lipid droplets (LDs) provide an "on-demand" source of fatty acids (FAs) that can be
mobilized in response to fluctuations in nutrient abundance. Surprisingly, the amount of LDs …

Abstract Treatment with therapy targeting BRAF and MEK (BRAF/MEK) has revolutionized
care in melanoma and other cancers; however, therapeutic resistance is common and …

Imaging of nucleic acids is important for studying cellular processes such as cell division and
apoptosis. A noninvasive label‐free technique is attractive. Raman spectroscopy provides …

Mitochondria control eukaryotic cell fate by producing the energy needed to support life and
the signals required to execute programed cell death. The biochemical milieu is known to …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer that has remained
clinically challenging to manage. Here we employ an RNAi-based in vivo functional genomics …

Longevity is dictated by a combination of environmental and genetic factors. One of the key
mechanisms to regulate life-span extension is the induction of protein chaperones for protein …

In multicellular organisms, neurons integrate a diverse array of external cues to affect
downstream changes in organismal health. Specifically, activation of the endoplasmic reticulum (…

There are many studies suggesting an age-associated decline in the actin cytoskeleton,
and this has been adopted as common knowledge in the field of aging biology. However, a …

In mouse embryos at mid-gestation, primordial germ cells (PGCs) undergo licensing to
become gametogenesis-competent cells (GCCs), gaining the capacity for meiotic initiation and …