▪ Abstract In addition to CD4, the human immunodeficiency virus (HIV) requires a coreceptor
for entry into target cells. The chemokine receptors CXCR4 and CCR5, members of the G …

Human interferon-inducible protein 10 (IP-10), a member of the alpha chemokine family,
inhibits bone marrow colony formation, has antitumor activity in vivo, is chemoattractant for …

Some pathways of T cell differentiation are associated with characteristic patterns of chemokine
receptor expression. A new lineage of effector/memory CD4+ T cells has been identified …

CC-chemokine receptor (CCR) 6 is the only known receptor for macrophage inflammatory
protein (MIP)-3α, a CC chemokine chemotactic for lymphocytes and dendritic cells. Using anti-…

β-Defensins are small antimicrobial peptides of the innate immune system produced in
response to microbial infection of mucosal tissue and skin. We demonstrate that murine β-…

Mig and IP-10 are related members of the CXC subfamily of the chemokine family of cytokines.
The murine Mig (MuMig), human IP-10, and the mouse homologue of IP-10, Crg-2, were …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

We sought to define protective mechanisms of immunity to Staphylococcus aureus and Candida
albicans bloodstream infections in mice immunized with the recombinant N-terminus of …

Mig is a chemokine of the CXC subfamily that was discovered by differential screening of a
cDNA library prepared from lymphokine-activated macrophages. The mig gene is inducible in …

Expression of a dominant negative mutant IFNγR1 in murine SCK and K1735 tumor cells
rendered them relatively unresponsive to IFNγ in vitro and more tumorigenic and less …