User profiles for Joshua J. Gooley
 | Joshua J. GooleyDuke-NUS Medical School Verified email at nus.edu.sg Cited by 11330 |
[HTML][HTML] Melanopsin in cells of origin of the retinohypothalamic tract
All known eukaryotic organisms exhibit physiological and behavioral rhythms termed
circadian rhythms that cycle with a near-24-hour period; in mammals, light is the most potent …
circadian rhythms that cycle with a near-24-hour period; in mammals, light is the most potent …
Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans
JJ Gooley, K Chamberlain, KA Smith… - The Journal of …, 2011 - academic.oup.com
… *Address all correspondence and requests for reprints to: Joshua J. Gooley, Ph.D., Division
of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, 221 …
of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, 221 …
Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback
This mini-review article presents the remarkable progress that has been made in the past
decade in our understanding of the neural circuitry underlying the regulation of sleep-wake …
decade in our understanding of the neural circuitry underlying the regulation of sleep-wake …
Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms
The suprachiasmatic nucleus (SCN) contains the brain's circadian pacemaker, but
mechanisms by which it controls circadian rhythms of sleep and related behaviors are poorly …
mechanisms by which it controls circadian rhythms of sleep and related behaviors are poorly …
A broad role for melanopsin in nonvisual photoreception
The rod and cone photoreceptors that mediate visual phototransduction in mammals are not
required for light-induced circadian entrainment, negative masking of locomotor activity, …
required for light-induced circadian entrainment, negative masking of locomotor activity, …
A neural mechanism for exacerbation of headache by light
The perception of migraine headache, which is mediated by nociceptive signals transmitted
from the cranial dura mater to the brain, is uniquely exacerbated by exposure to light. We …
from the cranial dura mater to the brain, is uniquely exacerbated by exposure to light. We …
Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light
JJ Gooley, SMW Rajaratnam, GC Brainard… - Science translational …, 2010 - science.org
In humans, modulation of circadian rhythms by light is thought to be mediated primarily by
melanopsin-containing retinal ganglion cells, not rods or cones. Melanopsin cells are …
melanopsin-containing retinal ganglion cells, not rods or cones. Melanopsin cells are …
The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms
Circadian rhythms of behavior and physiology can be entrained by daily cycles of restricted
food availability, but the pathways that mediate food entrainment are unknown. The …
food availability, but the pathways that mediate food entrainment are unknown. The …
[PDF][PDF] Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina
As the ear has dual functions for audition and balance, the eye has a dual role in detecting
light for a wide range of behavioral and physiological functions separate from sight [1–11]. …
light for a wide range of behavioral and physiological functions separate from sight [1–11]. …
Sleep and circadian rhythms in humans
CA Czeisler, JJ Gooley - Cold Spring Harbor symposia on …, 2007 - symposium.cshlp.org
During the past 50 years, converging evidence reveals that the fundamental properties of the
human circadian system are shared in common with those of other organisms. Concurrent …
human circadian system are shared in common with those of other organisms. Concurrent …