User profiles for Joshua K. Michener
Joshua K. MichenerORNL Verified email at ornl.gov Cited by 1050 |
High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch
JK Michener, CD Smolke - Metabolic engineering, 2012 - Elsevier
Metabolic engineering can produce a wide range of bulk and fine chemicals using renewable
resources. These approaches frequently require high levels of activity from multiple …
resources. These approaches frequently require high levels of activity from multiple …
Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways
JK Michener, K Thodey, JC Liang, CD Smolke - Metabolic engineering, 2012 - Elsevier
Cells are filled with biosensors, molecular systems that measure the state of the cell and
respond by regulating host processes. In much the same way that an engineer would monitor a …
respond by regulating host processes. In much the same way that an engineer would monitor a …
[HTML][HTML] PeakDecoder enables machine learning-based metabolite annotation and accurate profiling in multidimensional mass spectrometry measurements
…, D Tanjore, J Gardner, RD Smith, JK Michener… - Nature …, 2023 - nature.com
Multidimensional measurements using state-of-the-art separations and mass spectrometry
provide advantages in untargeted metabolomics analyses for studying biological and …
provide advantages in untargeted metabolomics analyses for studying biological and …
[HTML][HTML] Engineered Pseudomonas putida simultaneously catabolizes five major components of corn stover lignocellulose: Glucose, xylose, arabinose, p-coumaric …
…, M O'Brien, DM Klingeman, K Gorday, JK Michener… - Metabolic …, 2020 - Elsevier
Valorization of all major lignocellulose components, including lignin, cellulose, and
hemicellulose is critical for an economically viable bioeconomy. In most biochemical conversion …
hemicellulose is critical for an economically viable bioeconomy. In most biochemical conversion …
Ecosystem consequences of introducing plant growth promoting rhizobacteria to managed systems and potential legacy effects
The rapidly growing industry of crop biostimulants leverages the application of plant growth
promoting rhizobacteria (PGPR) to promote plant growth and health. However, introducing …
promoting rhizobacteria (PGPR) to promote plant growth and health. However, introducing …
Microbial assimilation of lignin-derived aromatic compounds and conversion to value-added products
… links open overlay panel Christopher C Azubuike , Marco N Allemann , Joshua K Michener
… Katahira, DC Garcia, SJ Haugen, KJ Ramirez, RJ Giannone, GT Beckham, JK Michener …
… Katahira, DC Garcia, SJ Haugen, KJ Ramirez, RJ Giannone, GT Beckham, JK Michener …
Identification and treatment of heme depletion attributed to overexpression of a lineage of evolved P450 monooxygenases
JK Michener, J Nielsen… - Proceedings of the …, 2012 - National Acad Sciences
Recent advances in metabolic engineering have demonstrated that microbial biosynthesis
can provide a viable alternative to chemical synthesis for the production of bulk and fine …
can provide a viable alternative to chemical synthesis for the production of bulk and fine …
Construction and optimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli enables bioconversion of model aromatic compounds
The production of biofuels from lignocellulose yields a substantial lignin by-product stream
that currently has few applications. Biological conversion of lignin-derived compounds into …
that currently has few applications. Biological conversion of lignin-derived compounds into …
Plant–Microbe Interactions: From Genes to Ecosystems Using Populus as a Model System
…, MJ Doktycz, J Labbé, JK Michener… - Phytobiomes …, 2021 - Am Phytopath Society
Plant–microbe symbioses span a continuum from pathogenic to mutualistic, with functional
consequences for both organisms in the symbiosis. In order to increase sustainable food and …
consequences for both organisms in the symbiosis. In order to increase sustainable food and …
Rapid, parallel identification of catabolism pathways of lignin-derived aromatic compounds in Novosphingobium aromaticivorans
…, DC Garcia, RJ Giannone, JK Michener - Applied and …, 2018 - Am Soc Microbiol
Transposon mutagenesis is a powerful technique in microbial genetics for the identification
of genes in uncharacterized pathways. Recently, the throughput of transposon mutagenesis …
of genes in uncharacterized pathways. Recently, the throughput of transposon mutagenesis …