In the last several decades polybrominated diphenyl ethers (PBDEs) have replaced the
previously banned polychlorinated biphenyls (PCBs) in multiple flame retardant utilities. As …

Per- and polyfluoroalkyl substances (PFASs) represent a highly ubiquitous group of
synthetic chemicals used in products ranging from water and oil repellents and lubricants to …

The contribution of environmental toxicants to the etiology and risk of Parkinson's disease (PD)
has been clearly established, with organochlorine insecticides routinely shown to …

Cilia defects have been implicated in a variety of human diseases and genetic disorders,
but how cilia motility contributes to these phenotypes is still unknown. To further our …

Sperm counts have rapidly declined in Western males over the past four decades. This rapid
decline remains largely unexplained, but exposure to environmental toxicants provides one …

Environmental influences and insults by reproductive toxicant exposure can lead to impaired
spermatogenesis or infertility. Understanding how toxicants disrupt spermatogenesis is …

N‐methyl‐D‐aspartate receptors (NMDARs) are ion channels comprising tetrameric assemblies
of GluN1 and GluN2 receptor subunits that mediate excitatory neurotransmission in the …

Impairments in the vesicular packaging of dopamine result in an accumulation of dopamine
in the cytosol. Cytosolic dopamine is vulnerable to two metabolic processes—enzymatic …

Over the last several decades, the use of halogenated organic compounds has become the
cause of environmental and human health concerns. Of particular notoriety has been the …

… Joshua M Bradner … Following data extraction and filtering, 6,028 metabolite peaks were
detected and measured in the CSF of patients and 7,249 m/z features in plasma. After controlling …