ALG-5 is a miRNA-associated Argonaute required for proper developmental timing in the Caenorhabditis elegans germline

KC Brown, JM Svendsen, RM Tucci… - Nucleic acids …, 2017 - academic.oup.com
Caenorhabditis elegans contains 25 Argonautes, of which, ALG-1 and ALG-2 are known to
primarily interact with miRNAs. ALG-5 belongs to the AGO subfamily of Argonautes that …

Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans

KJ Reed, JM Svendsen, KC Brown… - Nucleic acids …, 2020 - academic.oup.com
Piwi-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) are distinct classes of
small RNAs required for proper germline development. To identify the roles of piRNAs and …

Combining tRNA sequencing methods to characterize plant tRNA expression and post-transcriptional modification

…, G Hummel, NL Coots, JM Svendsen… - RNA biology, 2021 - Taylor & Francis
Differences in tRNA expression have been implicated in a remarkable number of biological
processes. There is growing evidence that tRNA genes can play dramatically different roles …

[PDF][PDF] Henn-1/HEN1 promotes germline immortality in Caenorhabditis elegans

JM Svendsen, KJ Reed, T Vijayasarathy… - Cell reports, 2019 - cell.com
The germline contains an immortal cell lineage that ensures the faithful transmission of genetic
and, in some instances, epigenetic information from one generation to the next. Here, we …

Mitochondrial mutations in Caenorhabditis elegans show signatures of oxidative damage and an AT-bias

G Waneka, JM Svendsen, JC Havird, DB Sloan - Genetics, 2021 - academic.oup.com
Rapid mutation rates are typical of mitochondrial genomes (mtDNAs) in animals, but it is not
clear why. The difficulty of obtaining measurements of mtDNA mutation that are not biased …

Vaccination against the M protein of Streptococcus pyogenes prevents death after influenza virus: S. pyogenes super-infection

…, BA Juber, MJ Schuneman, TE Bickett, JM Svendsen… - Vaccine, 2014 - Elsevier
Influenza virus infections are associated with a significant number of illnesses and deaths
on an annual basis. Many of the deaths are due to complications from secondary bacterial …

Contributions of Influenza Virus Hemagglutinin and Host Immune Responses Toward the Severity of Influenza Virus: Streptococcus pyogenes Superinfections

JM Klonoski, T Watson, TE Bickett, JM Svendsen… - Viral …, 2018 - liebertpub.com
Influenza virus infections can be complicated by bacterial superinfections, which are medically
relevant because of a complex interaction between the host, the virus, and the bacteria. …

[PDF][PDF] piRNA rules of engagement

JM Svendsen, TA Montgomery - Developmental Cell, 2018 - cell.com
piRNAs are known to silence transposable elements, but not all piRNAs match transposon
sequences. Recent studies from Shen et al. (2018) and Zhang et al. (2018) identify rules for …

Strategy and disproportionality in contemporary conflicts

ADM Svendsen - The Journal of Strategic Studies, 2010 - Taylor & Francis
This article examines ‘disproportionality’. It begins by tabling some suggestions for how greater
‘proportionality’ can be attained and then maintained, particularly in international security …

Limitations in health-care system resources affecting adherence of patient with psoriasis to topical drugs: a focus group study

MT Svendsen, SR Feldman… - Journal of Psoriasis …, 2020 - journals.sagepub.com
Background: Topical therapy is first-line treatment for patients with mild-to-moderate psoriasis,
but low adherence to topical drugs is a barrier to treatment success. Health-care system …