The Omicron, or Pango lineage B.1.1.529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
do not necessarily develop PCR or antibody positivity, suggesting that some …

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis
in children have been reported worldwide, including 278 cases in the UK 1 . Here we report …

Understanding the nature of immunity following mild/asymptomatic infection with SARS-CoV-2
is crucial to controlling the pandemic. We analyzed T cell and neutralizing antibody …

Background We hypothesised that host-response biomarkers of viral infections might
contribute to early identification of individuals infected with SARS-CoV-2, which is critical to …

Effective control of SARS-CoV-2 infection on primary exposure may reveal correlates of
protective immunity to future variants, but we lack insights into immune responses before or at …

Host immune responses at the site of Mycobacterium tuberculosis infection can mediate
pathogenesis of tuberculosis (TB) and onward transmission of infection. We hypothesized that …

SARS‐CoV‐2 infection results in different outcomes ranging from asymptomatic infection to
mild or severe disease and death. Reasons for this diversity of outcome include differences …

T cell responses precede antibody and may provide early control of infection. We analyzed
the clonal basis of this rapid response following SARS-COV-2 infection. We applied T cell …

Evaluation of host-response blood transcriptional signatures of viral infection have so far
failed to test whether these biomarkers reflect different biological processes that may be …