Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has
been a formidable challenge. Adopting a genome-wide association strategy, we genotyped …

To identify previously unknown genetic loci associated with fasting glucose concentrations,
we examined the leading association signals in ten genome-wide association scans …

Given the anthropometric differences between men and women and previous evidence of
sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic …

Genome-wide association studies (GWAS) have identified ∼100 loci associated with blood
lipid levels, but much of the trait heritability remains unexplained, and at most loci the …

Identifying the genetic variants that regulate fasting glucose concentrations may further our
understanding of the pathogenesis of diabetes. We therefore investigated the association of …

Type 2 diabetes (T2D) results from the combined effects of genetic and environmental factors
on multiple tissues over time. Of the >100 variants associated with T2D and related traits in …

We integrate comeasured gene expression and DNA methylation (DNAme) in 265 human
skeletal muscle biopsies from the FUSION study with >7 million genetic variants and eight …

Objectives Present study examines the relationship between the estimated risk of
developing type 2 diabetes (T2D) and health-related quality of life (HRQoL). We quantify the …

Purpose To examine the general health status and health-related quality of life (HRQOL)
along the diabetes continuum of middle-aged and older Finns, and to determine the glucose …

There is a wide variation in the development and course of erectile dysfunction (ED) in men,
which confirms the need for prospective studies. We conducted a cross-sectional analysis …