The chemokine Cxcl12 binds Cxcr4 and Cxcr7 receptors to control cell migration in multiple
biological contexts, including brain development, leukocyte trafficking, and tumorigenesis. …

Functioning of the cerebral cortex requires the coordinated assembly of circuits involving
glutamatergic projection neurons and GABAergic interneurons. Although much is known about …

Through analysis of the Drosophila ionotropic receptors (IRs), a family of variant ionotropic
glutamate receptors, we reveal that most IRs are expressed in peripheral neuron populations …

Textural properties provide information on the ingestibility, digestibility and state of ripeness
or decay of sources of nutrition. Compared with our understanding of the chemosensory …

CXCL12/CXCR4 signaling has been reported to regulate three essential processes for the
establishment of neural networks in different neuronal systems: neuronal migration, cell …

Chemosensory tissues exhibit significant between-species variability, yet the evolution of
gene expression and cell types underlying this diversity remain poorly understood. To address …

Neural circuits in the cerebral cortex consist of excitatory pyramidal cells and inhibitory
interneurons. These two main classes of cortical neurons follow largely different genetic programs…

Among individuals, behavioral differences result from the well-known interplay of nature and
nurture. Minute differences in the genetic code can lead to differential gene expression and …

Chemosensation and mechanosensation cover an enormous spectrum of processes by
which animals use information from the environment to adapt their behavior. For pragmatic …

The migratory route of neural progenitor/precursor cells (NPC) has a central role in central
nervous system development. Although the role of the chemokine CXCL12 in NPC migration …