Phase separation of mixtures of oppositely charged polymers provides a simple and direct
route to compartmentalisation via complex coacervation, which may have been important for …

It has long been proposed that phase-separated compartments can provide a basis for the
formation of cellular precursors in prebiotic environments. However, we know very little about …

Conspectus Traditional cell biological techniques are not readily suitable for studying lipid
signaling events because genetic perturbations are much slower than the interconversion of …

We investigate intrinsically disordered regions (IDRs) of phase separating proteins regarding
their impact on liquid-liquid phase separation (LLPS) of the full protein. Our theoretical …

Adenosine triphosphate (ATP) production and utilization is critically important for animal
development. How these processes are regulated in space and time during tissue growth …

Studying the role of molecularly distinct lipid species in cell signaling remains challenging
due to a scarcity of methods for performing quantitative lipid biochemistry in living cells. We …

Studying the role of molecularly distinct lipid species in cell signaling remains challenging
due to a scarcity of methods for performing quantitative lipid biochemistry in living cells. We …

Recent progress in glycan research has been driven by widespread implementations of
metabolic oligosaccharide engineering. Complementing existing approaches, we here …

In cell division, mitosis is the phase in which duplicated sets of chromosomes are mechanically
aligned to form the metaphase plate before being segregated in two daughter cells. …

Neurodegeneràve diseases such as amyotrophic lateral sclerosis (ALS) are oten associated
with mutàons in proteins that are associated with stress granules. Stress granules are …