Objectives: To find and validate generalizable sepsis subtypes using data-driven clustering.
Design: We used advanced informatics techniques to pool data from 14 bacterial sepsis …

Improved risk stratification and prognosis prediction in sepsis is a critical unmet need. Clinical
severity scores and available assays such as blood lactate reflect global illness severity …

Improved risk stratification and prognosis in sepsis is a critical unmet need. Clinical severity
scores and available assays such as blood lactate reflect global illness severity with …

Background Sepsis is defined as a dysregulated immune response, but no immunomodulatory
therapies have been shown to decrease sepsis mortality. Despite its high clinical …

… A study at our institution (Howrylak et al., 2014), indicated that among caregivers who reported
no … Howrylak JA, Spanier AJ, Huang B, et al. Cotinine in children admitted for asthma and …

Introduction The purpose of this study was to examine the relationships between screening
questions for secondhand smoke (SHS) exposure and biomarker results using hair nicotine …

… The student (Judy Howrylak, a high school senior) responded to the following prompt: …
Judith Fishman reminds us that "telling a story is not only one of the oldest forms of …

OBJECTIVES: Documentation of children’s tobacco smoke exposure (TSE) in the electronic
health record (EHR) can have important implications for clinical care. However, it may not be …

Background Tobacco use results in exposure to nicotine, a powerfully addictive substance,
often leading to tobacco dependence. Tobacco dependence is considered a pediatric …

This technical report serves to provide the evidence base for the American Academy of
Pediatrics’ policy statements “Clinical Practice Policy to Protect Children From Tobacco, Nicotine, …