[HTML][HTML] Human recombinant soluble ACE2 in severe COVID-19

A Zoufaly, M Poglitsch, JH Aberle… - The Lancet …, 2020 - thelancet.com
Judith H Aberle, MD Judith H Aberle … We also observed soluble ACE2 present in tracheal
fluid throughout the observation period, showing an increase towards day 6 that peaked 36 h …

SARS-CoV-2 vaccination in rituximab-treated patients: B cells promote humoral immune responses in the presence of T-cell-mediated immunity

…, S Winkler, S Blüml, K Stiasny, JH Aberle… - Annals of the …, 2021 - ard.bmj.com
Objectives Evidence suggests that B cell-depleting therapy with rituximab (RTX) affects
humoral immune response after vaccination. It remains unclear whether RTX-treated patients …

Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2

…, MD Nicholson, T Penz, D Schmid, SW Aberle… - Science translational …, 2020 - science.org
Superspreading events shaped the coronavirus disease 2019 (COVID-19) pandemic, and
their rapid identification and containment are essential for disease control. Here, we provide a …

Comparison of SARS-CoV-2 antibody response 4 weeks after homologous vs heterologous third vaccine dose in kidney transplant recipients: a randomized clinical …

…, L Weseslindtner, A Indra, JH Aberle… - JAMA internal …, 2022 - jamanetwork.com
Importance Fewer than 50% of kidney transplant recipients (KTRs) develop antibodies
against the SARS-CoV-2 spike protein after 2 doses of an mRNA vaccine. Preliminary data …

SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses

…, V Mühlgrabner, M Graninger, SW Aberle… - Science …, 2021 - science.org
CD8 + T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus
control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8 + T cell …

Single versus dual respiratory virus infections in hospitalized infants: Impact on clinical course of disease and interferon-γ response

JH Aberle, SW Aberle, E Pracher… - The Pediatric …, 2005 - journals.lww.com
Background: Dual respiratory viral infections are frequently associated with lower respiratory
tract illness in infants. This study aimed to determine the impact of a dual respiratory viral …

[HTML][HTML] ACE2 elevation in severe COVID-19

…, D Bonderman, R Strassl, JH Aberle… - American journal of …, 2021 - atsjournals.org
Methods We measured enzymatically active plasma ACE2 concentration (subsequently
referred to as “ACE2”) and key RAS metabolites in 532 blood samples obtained from 126 …

Effectiveness of reverse transcription-PCR, virus isolation, and enzyme-linked immunosorbent assay for diagnosis of influenza A virus infection in different age groups

…, M Kundi, SW Aberle, JH Aberle… - Journal of clinical …, 2002 - Am Soc Microbiol
The degrees of effectiveness of reverse transcription (RT)-PCR, virus isolation, and antigen
enzyme-linked immunosorbent assay (ELISA) for the detection of influenza A virus were …

Reduced interferon-γ expression in peripheral blood mononuclear cells of infants with severe respiratory syncytial virus disease

JH Aberle, SW Aberle, MN Dworzak… - American journal of …, 1999 - atsjournals.org
We examined the in vivo cell-mediated immune response in infants with respiratory syncytial
virus (RSV) infection in order to gain information about the pathogenesis of severe RSV …

In vitro-synthesized infectious RNA as an attenuated live vaccine in a flavivirus model

CW Mandl, JH Aberle, SW Aberle, H Holzmann… - Nature medicine, 1998 - nature.com
Live virus vaccines have in many cases proven to be an extremely effective tool for the
prevention of viral diseases 1, 2. However, the production of conventional live vaccines in …