The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literature

…, L Dabbagh, M Pasdar, JC Hugh - … International Journal of …, 2001 - Wiley Online Library
BACKGROUND The MUC1 mucin is present on the apical surface of normal secretory
epithelia. In breast carcinoma, MUC1 expression is variable in amount and cellular localization, …

Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group

…, J Cuzick, M Ellis, NL Henry, JC Hugh… - Journal of the …, 2011 - academic.oup.com
Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical
assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the …

[HTML][HTML] Adjuvant docetaxel for node-positive breast cancer

…, D Walde, A Rodriguez-Lescure, J Hugh… - … England Journal of …, 2005 - Mass Medical Soc
Background We compared docetaxel plus doxorubicin and cyclophosphamide (TAC) with
fluorouracil plus doxorubicin and cyclophosphamide (FAC) as adjuvant chemotherapy for …

An international Ki67 reproducibility study

…, LM McShane, D Gao, JC Hugh… - Journal of the …, 2013 - academic.oup.com
Background In breast cancer, immunohistochemical assessment of proliferation using the
marker Ki67 has potential use in both research and clinical management. However, lack of …

[HTML][HTML] Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial

J Hugh, J Hanson, MCU Cheang… - Journal of clinical …, 2009 - ncbi.nlm.nih.gov
Purpose To investigate the prognostic and predictive significance of subtyping node-positive
early breast cancer by immunohistochemistry in a clinical trial of a docetaxel-containing …

[PDF][PDF] Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer

…, R Sinha, J Hanson, N Chauhan, J Hugh… - Journal of Clinical …, 2006 - academia.edu
Purpose As survival in breast cancer patients is improving, brain metastases are becoming
increasingly prevalent. The risk of brain metastases in newly diagnosed human epidermal …

Primary breast lymphoma: an immunohistologic study of 20 new cases

JC Hugh, FI Jackson, J Hanson, S Poppema - Cancer, 1990 - Wiley Online Library
Primary malignant lymphomas of the breast (PBL) are uncommon. the authors report the
clinical, histologic, and immunoperoxidase findings on 20 cases recorded at the Alberta Cancer …

[HTML][HTML] An international study to increase concordance in Ki67 scoring

…, AM Gown, D Grabau, C Gutierrez, JC Hugh… - Modern …, 2015 - nature.com
Although an important biomarker in breast cancer, Ki67 lacks scoring standardization, which
has limited its clinical use. Our previous study found variability when laboratories used their …

Adjuvant docetaxel, doxorubicin, and cyclophosphamide in node-positive breast cancer: 10-year follow-up of the phase 3 randomised BCIRG 001 trial

…, K Laing, D Walde, C Price, JC Hugh… - The Lancet …, 2013 - thelancet.com
Background We compared standard adjuvant anthracycline chemotherapy with
anthracycline–taxane combination chemotherapy in women with operable node-positive breast …

Genitourinary small cell carcinoma: determination of clinical and therapeutic factors associated with survival

JR MACKEY, HJ AU, J HUGH, P VENNER - The Journal of urology, 1998 - Elsevier
PURPOSE: We assessed the prognostic impact of genitourinary small cell carcinoma tumor
and patient characteristics, and therapy. MATERIALS AND METHODS: We retrospectively …