Characterization of a functional NF-κB site in the human interleukin 1β promoter: evidence for a positive autoregulatory loop
…, A Roulston, IVY Kwan, N Pepin, J Lacoste… - … and cellular biology, 1993 - Taylor & Francis
The -300 region of the interleukin 1β (IL-1β) promoter contains a functional NF-κB binding
site composed of the decamer sequence 5'-GGGAAAATCC-3'. Probes representing the -300 …
site composed of the decamer sequence 5'-GGGAAAATCC-3'. Probes representing the -300 …
Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.
A Kumar, J Haque, J Lacoste… - Proceedings of the …, 1994 - National Acad Sciences
The induction of interferon (IFN) genes by viruses or double-stranded RNA (dsRNA) requires
the assembly of a complex set of transcription factors on responsive DNA elements of IFN …
the assembly of a complex set of transcription factors on responsive DNA elements of IFN …
Live-cell microscopy–tips and tools
MM Frigault, J Lacoste, JL Swift… - Journal of cell …, 2009 - journals.biologists.com
Imaging of living cells and tissue is now common in many fields of the life and physical
sciences, and is instrumental in revealing a great deal about cellular dynamics and function. It is …
sciences, and is instrumental in revealing a great deal about cellular dynamics and function. It is …
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKε molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage
Intracellular RNA virus infection is detected by the cytoplasmic RNA helicase RIG-I that plays
an essential role in signaling to the host antiviral response. Recently, the adapter molecule …
an essential role in signaling to the host antiviral response. Recently, the adapter molecule …
RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I
M Solis, P Nakhaei, M Jalalirad, J Lacoste… - Journal of …, 2011 - Am Soc Microbiol
The rapid induction of type I interferon (IFN) is essential for establishing innate antiviral
responses. During infection, cytoplasmic viral RNA is sensed by two DExD/H box RNA helicases, …
responses. During infection, cytoplasmic viral RNA is sensed by two DExD/H box RNA helicases, …
QUAREP‐LiMi: A community‐driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy
…, N Kobayashi, G Krens, S Kunis, J Lacoste… - Journal of …, 2021 - Wiley Online Library
A modern day light microscope has evolved from a tool devoted to making primarily empirical
observations to what is now a sophisticated , quantitative device that is an integral part of …
observations to what is now a sophisticated , quantitative device that is an integral part of …
Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model
Rigorous record-keeping and quality control are required to ensure the quality, reproducibility
and value of imaging data. The 4DN Initiative and BINA here propose light Microscopy …
and value of imaging data. The 4DN Initiative and BINA here propose light Microscopy …
Ubiquitin-regulated recruitment of IκB kinase ε to the MAVS interferon signaling adapter
…, M Vilasco, M Arguello, Q Sun, J Lacoste… - … and cellular biology, 2009 - Taylor & Francis
Induction of the antiviral interferon response is initiated upon recognition of viral RNA
structures by the RIG-I or Mda-5 DEX(D/H) helicases. A complex signaling cascade then …
structures by the RIG-I or Mda-5 DEX(D/H) helicases. A complex signaling cascade then …
Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase
K Nolan, J Lacoste, JT Parsons - Molecular and cellular biology, 1999 - Am Soc Microbiol
Focal adhesion kinase (FAK) has been implicated in cellular processes that control cell
adhesion, migration, cell cycle progression, and apoptosis. FRNK (FAK-related nonkinase) is the …
adhesion, migration, cell cycle progression, and apoptosis. FRNK (FAK-related nonkinase) is the …
[HTML][HTML] Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications
…, MS Itano, DP Keeley, S Kunis, J Lacoste… - Nature …, 2021 - nature.com
For quality, interpretation, reproducibility and sharing value, microscopy images should be
accompanied by detailed descriptions of the conditions that were used to produce them. Micro…
accompanied by detailed descriptions of the conditions that were used to produce them. Micro…