Several risk factors for Crohn's disease have been identified in recent genome-wide association
studies. To advance gene discovery further, we combined data from three studies on …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…

Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

More than 1,000 susceptibility loci have been identified through genome-wide association
studies (GWAS) of common variants; however, the specific genes and full allelic spectrum of …

Genomics and the Multifactorial Nature of Human Autoimmune Disease | NEJM Skip to main
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Ulcerative colitis is a chronic, relapsing inflammatory condition of the gastrointestinal tract
with a complex genetic and environmental etiology. In an effort to identify genetic variation …

Inflammatory bowel diseases are chronic gastrointestinal inflammatory disorders that affect
millions of people worldwide. Genome-wide association studies have identified 200 …

Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is
thought to result from the effect of environmental factors in a genetically predisposed host. A …

The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic
disorders that cause abdominal pain, diarrhea, and gastrointestinal bleeding. To identify …

Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …