Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost
200,000 people worldwide each year. It is acquired when mammalian hosts inhale the …

Cryptococcus neoformans is a basidiomycetous yeast and the cause of cryptococcosis in
immunocompromised individuals. The most severe form of the disease is meningoencephalitis, …

Aim: We investigated the involvement of the autophagy protein 7 (Atg7) in physiology and
pathogenic potential of Cryptococcus neoformans. Materials & methods: The C. neoformans …

Adaptation to the host environment is crucial for fungal pathogenesis. Calcium (Ca 2+ ) signals
are essential for fungal cells to respond rapidly to stress stimuli. In eukaryotic cells, Ca 2+ …

The Cryptococcus gattii species complex harbors the main etiological agents of cryptococcosis
in immunocompetent patients. C. gattii molecular type VGII predominates in the north and …

Melanin formation is a promising target for antifungal development. We screened a collection
of 727 compounds that were previously approved for clinical use in humans for inhibition of …

The regulation of virulence factor production and deployment is crucial for the establishment
of microbial infection and subsequent pathogenesis. If these processes are not properly …

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost
200,000 people worldwide each year. It is acquired when mammalian hosts inhale the …

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost 2
200,000 people worldwide each year. It is acquired when mammalian hosts inhale the 3 …

Calcium-permeable, stretch-activated nonselective cation (SA Cat) channels mediate cellular
responses to mechanical stimuli. However, genes encoding such channels have not been …