User profiles for Julia E Maxson
 | Julia MaxsonAssistant Professor, OHSU Verified email at ohsu.edu Cited by 2312 |
[HTML][HTML] Oncogenic CSF3R Mutations in Chronic Neutrophilic Leukemia and Atypical CML
JE Maxson, J Gotlib, DA Pollyea… - … England Journal of …, 2013 - Mass Medical Soc
Background The molecular causes of many hematologic cancers remain unclear. Among
these cancers are chronic neutrophilic leukemia (CNL) and atypical (BCR-ABL1–negative) …
these cancers are chronic neutrophilic leukemia (CNL) and atypical (BCR-ABL1–negative) …
[PDF][PDF] Integrative analysis of drug response and clinical outcome in acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of myeloid-lineage cells with limited therapeutic
options. We previously combined ex vivo drug sensitivity with genomic, transcriptomic, and …
options. We previously combined ex vivo drug sensitivity with genomic, transcriptomic, and …
The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment
Although activation of tyrosine kinase pathways is a shared theme among myeloproliferative
neoplasms, the pathogenetic basis of chronic neutrophilic leukemia (CNL) has remained …
neoplasms, the pathogenetic basis of chronic neutrophilic leukemia (CNL) has remained …
The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition
AG Fleischman, JE Maxson, SB Luty… - Blood, The Journal …, 2013 - ashpublications.org
We have recently identified targetable mutations in CSF3R (GCSFR) in 60% of chronic
neutrophilic leukemia (CNL) and atypical (BCR-ABL–negative) chronic myeloid leukemia (aCML) …
neutrophilic leukemia (CNL) and atypical (BCR-ABL–negative) chronic myeloid leukemia (aCML) …
[HTML][HTML] Cancer-and endotoxin-induced cachexia require intact glucocorticoid signaling in skeletal muscle
…, M Szumowski, XX Zhu, JE Maxson… - The FASEB …, 2013 - ncbi.nlm.nih.gov
Cachexia is a wasting condition defined by skeletal muscle atrophy in the setting of systemic
inflammation. To explore the site at which inflammatory mediators act to produce atrophy in …
inflammation. To explore the site at which inflammatory mediators act to produce atrophy in …
Efficacy of ruxolitinib in patients with chronic neutrophilic leukemia and atypical chronic myeloid leukemia
…, J Dunlap, Y Chen, C Degnin, JE Maxson… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Colony-stimulating factor-3 receptor (CSF3R)-T618I is a recurrent activating
mutation in chronic neutrophilic leukemia (CNL) and to a lesser extent in atypical chronic …
mutation in chronic neutrophilic leukemia (CNL) and to a lesser extent in atypical chronic …
Genomics of chronic neutrophilic leukemia
JE Maxson, JW Tyner - Blood, The Journal of the American …, 2017 - ashpublications.org
Chronic neutrophilic leukemia (CNL) is a distinct myeloproliferative neoplasm with a high
prevalence (>80%) of mutations in the colony-stimulating factor 3 receptor (CSF3R). These …
prevalence (>80%) of mutations in the colony-stimulating factor 3 receptor (CSF3R). These …
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis
…, BJ Druker, SK McWeeney, JE Maxson… - Blood, The Journal …, 2019 - ashpublications.org
Chronic neutrophilic leukemia (CNL), atypical chronic myeloid leukemia (aCML), and
myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN-U) are a group of rare …
myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN-U) are a group of rare …
[HTML][HTML] Significant clinical response to JAK1/2 inhibition in a patient with CSF3R-T618I-positive atypical chronic myeloid leukemia
KHT Dao, MB Solti, JE Maxson, EF Winton… - Leukemia research …, 2014 - Elsevier
Mutations in CSF3R (colony-stimulating factor 3 receptor) are frequent oncogenic drivers in
chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML). Here …
chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML). Here …
[HTML][HTML] Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and …
JE Maxson, SB Luty, JD MacManiman, ML Abel… - Journal of Biological …, 2014 - ASBMB
Mutations in the CSF3 granulocyte colony-stimulating factor receptor CSF3R have recently
been found in a large percentage of patients with chronic neutrophilic leukemia and, more …
been found in a large percentage of patients with chronic neutrophilic leukemia and, more …