Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter
host cells. Here we show that the actin filament-binding protein coronin regulates gliding …

Cell motility is essential for protozoan and metazoan organisms and typically relies on the
dynamic turnover of actin filaments. In metazoans, monomeric actin polymerises into usually …

Malaria is a potentially fatal disease caused by Plasmodium parasites and poses a major
medical risk in large parts of the world. The development of new, affordable antimalarial drugs …

We report here that wild-type Escherichia coli grows on N-acetylmuramic acid (MurNAc) as
the sole source of carbon and energy. Analysis of mutants defective in N-acetylglucosamine (…

Malaria, caused by protozoan Plasmodium parasites, remains a prevalent infectious human
disease due to the lack of an efficient and safe vaccine. This is directly related to the …

Cyclase-associated proteins (CAPs) are evolutionary conserved G-actin-binding proteins
that regulate microfilament turnover. CAPs have a modular structure consisting of an N-…

Apicomplexan parasites, such as the malaria-causing Plasmodium, utilize an actin-based
motor for motility and host cell invasion. The actin filaments of these parasites are unusually …

Cerebral malaria is one of the most severe complications of malaria disease, attributed to a
complicated series of immune reactions in the host. The syndrome is marked by inflammatory …

The biological function of the post‐translational modification hypusine in the eukaryotic
initiation factor 5A ( EIF ‐5A) in eukaryotes is still not understood. Hypusine is formed by two …

Malaria is transmitted through the injection of Plasmodium sporozoites into the skin by
Anopheles mosquitoes. The parasites first replicate within the liver before infecting red blood cells…