FK506-binding protein 10, a potential novel drug target for idiopathic pulmonary fibrosis

…, IE Fernandez, L Knüppel, J Maul… - American journal of …, 2015 - atsjournals.org
Rationale: Increased abundance and stiffness of the extracellular matrix, in particular
collagens, is a hallmark of idiopathic pulmonary fibrosis (IPF). FK506-binding protein 10 (FKBP10) …

[HTML][HTML] The impact of gender and sex in psoriasis: What to be aware of when treating women with psoriasis

…, C Seeli, M Nina, LV Maul, JT Maul - International journal of …, 2022 - journals.lww.com
Background: Psoriasis is a common chronic inflammatory skin disease with an exceptionally
high burden for women. Objective: Sex-dependent differences in disease manifestation, …

Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment

J Matthias, J Maul, R Noster, H Meinl… - Science translational …, 2019 - science.org
The incidence of allergic diseases has increased over the past 50 years, likely due to
environmental factors. However, the nature of these factors and the mode of action by which they …

[HTML][HTML] Transient efficacy of tofacitinib in alopecia areata universalis

F Anzengruber, JT Maul, J Kamarachev… - Case reports in …, 2016 - karger.com
Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of
lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and …

[HTML][HTML] Effects of COVID-19 lockdown on melanoma diagnosis in Switzerland: increased tumor thickness in elderly females and shift towards stage IV melanoma …

L Kostner, SE Cerminara, GSP Pamplona, JT Maul… - Cancers, 2022 - mdpi.com
Simple Summary Concerns about potential diagnostic delays due to pandemic-related
disruptions were expressed early during the COVID-19 outbreak. In the present study, we …

[HTML][HTML] Over-detection of melanoma-suspect lesions by a CE-certified smartphone app: performance in comparison to dermatologists, 2D and 3D convolutional …

…, SE Cerminara, L Kostner, SM Huber, M Kunz, JT Maul… - Cancers, 2022 - mdpi.com
Simple Summary Early detection and resection of cutaneous melanoma are crucial for a
good prognosis. However, visual distinction of early melanomas from benign nevi remains …

Assessment of frequency of rosacea subtypes in patients with rosacea: a systematic review and meta-analysis

…, NKF Wienholtz, AS Halling, JT Maul… - JAMA …, 2022 - jamanetwork.com
Importance Four distinct rosacea subtypes have traditionally been recognized, but the frequency
of these subtypes among patients with rosacea remains unknown. Objective To assess …

Successful intra-class switching among IL-17 antagonists: a multicentre, multinational, retrospective study

…, K Papageorgiou, TO Meier, JT Maul… - Archives of …, 2019 - Springer
IL-17 blockers are among the newer anti-psoriatic treatment options and little is known about
the interclass switching. We have thus initiated a multi-center, multi-national, retrospective …

A distinct inhibitory function for miR-18a in Th17 cell differentiation

MM Montoya, J Maul, PB Singh, HH Pua… - The Journal of …, 2017 - journals.aai.org
Th17 cell responses orchestrate immunity against extracellular pathogens but also underlie
autoimmune disease pathogenesis. In this study, we uncovered a distinct and critical role for …

IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation

…, TS Phan, TM Kündig, MP Levesque, JT Maul… - Science …, 2021 - science.org
Psoriasis is a chronic inflammatory skin disorder underpinned by dysregulated cytokine
signaling. Drugs neutralizing the common p40 subunit of interleukin-12 (IL-12) and IL-23 …