User profiles for Julia Salzman
Julia SalzmanAssociate Professor, Stanford University Verified email at stanford.edu Cited by 10484 |
[HTML][HTML] Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types
Most human pre-mRNAs are spliced into linear molecules that retain the exon order defined
by the genomic sequence. By deep sequencing of RNA from a variety of normal and …
by the genomic sequence. By deep sequencing of RNA from a variety of normal and …
Circular RNA expression: its potential regulation and function
J Salzman - Trends in genetics, 2016 - cell.com
In 2012, a new feature of eukaryotic gene expression emerged: ubiquitous expression of
circular RNA (circRNA) from genes traditionally thought to express messenger or linear …
circular RNA (circRNA) from genes traditionally thought to express messenger or linear …
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans
Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …
[HTML][HTML] Cell-type specific features of circular RNA expression
Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at
many of these loci, the predominant RNA isoform is a circle. Using an improved …
many of these loci, the predominant RNA isoform is a circle. Using an improved …
Circular RNAs: analysis, expression and potential functions
SP Barrett, J Salzman - Development, 2016 - journals.biologists.com
Just a few years ago, it had been assumed that the dominant RNA isoforms produced from
eukaryotic genes were variants of messenger RNA, functioning as intermediates in gene …
eukaryotic genes were variants of messenger RNA, functioning as intermediates in gene …
[HTML][HTML] Circular RNA is expressed across the eukaryotic tree of life
An unexpectedly large fraction of genes in metazoans (human, mouse, zebrafish, worm, fruit
fly) express high levels of circularized RNAs containing canonical exons. Here we report …
fly) express high levels of circularized RNAs containing canonical exons. Here we report …
Detecting circular RNAs: bioinformatic and experimental challenges
L Szabo, J Salzman - Nature Reviews Genetics, 2016 - nature.com
The pervasive expression of circular RNAs (circRNAs) is a recently discovered feature of
gene expression in highly diverged eukaryotes. Numerous algorithms that are used to detect …
gene expression in highly diverged eukaryotes. Numerous algorithms that are used to detect …
[HTML][HTML] Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
Background The pervasive expression of circular RNA is a recently discovered feature of gene
expression in highly diverged eukaryotes, but the functions of most circular RNAs are still …
expression in highly diverged eukaryotes, but the functions of most circular RNAs are still …
Circular RNA biogenesis can proceed through an exon-containing lariat precursor
10.7554/eLife.07540.001 Pervasive expression of circular RNA is a recently discovered
feature of eukaryotic gene expression programs, yet its function remains largely unknown. The …
feature of eukaryotic gene expression programs, yet its function remains largely unknown. The …
Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome
Viruses are the most abundant known infectious agents on the planet and are significant
drivers of diversity in a variety of ecosystems. Although there have been numerous studies of …
drivers of diversity in a variety of ecosystems. Although there have been numerous studies of …