User profiles for Julia Salzman

Julia Salzman

Associate Professor, Stanford University
Verified email at stanford.edu
Cited by 10484

[HTML][HTML] Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types

J Salzman, C Gawad, PL Wang, N Lacayo, PO Brown - PloS one, 2012 - journals.plos.org
Most human pre-mRNAs are spliced into linear molecules that retain the exon order defined
by the genomic sequence. By deep sequencing of RNA from a variety of normal and …

Circular RNA expression: its potential regulation and function

J Salzman - Trends in genetics, 2016 - cell.com
In 2012, a new feature of eukaryotic gene expression emerged: ubiquitous expression of
circular RNA (circRNA) from genes traditionally thought to express messenger or linear …

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

…, MA Krasnow, AO Pisco, SR Quake, J Salzman… - Science, 2022 - science.org
Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …

[HTML][HTML] Cell-type specific features of circular RNA expression

J Salzman, RE Chen, MN Olsen, PL Wang… - PLoS …, 2013 - journals.plos.org
Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at
many of these loci, the predominant RNA isoform is a circle. Using an improved …

Circular RNAs: analysis, expression and potential functions

SP Barrett, J Salzman - Development, 2016 - journals.biologists.com
Just a few years ago, it had been assumed that the dominant RNA isoforms produced from
eukaryotic genes were variants of messenger RNA, functioning as intermediates in gene …

[HTML][HTML] Circular RNA is expressed across the eukaryotic tree of life

…, MN Olsen, JR Dinneny, PO Brown, J Salzman - PloS one, 2014 - journals.plos.org
An unexpectedly large fraction of genes in metazoans (human, mouse, zebrafish, worm, fruit
fly) express high levels of circularized RNAs containing canonical exons. Here we report …

Detecting circular RNAs: bioinformatic and experimental challenges

L Szabo, J Salzman - Nature Reviews Genetics, 2016 - nature.com
The pervasive expression of circular RNAs (circRNAs) is a recently discovered feature of
gene expression in highly diverged eukaryotes. Numerous algorithms that are used to detect …

[HTML][HTML] Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

…, C Jiang, MM Parast, CE Murry, LC Laurent, J Salzman - Genome biology, 2015 - Springer
Background The pervasive expression of circular RNA is a recently discovered feature of gene
expression in highly diverged eukaryotes, but the functions of most circular RNAs are still …

Circular RNA biogenesis can proceed through an exon-containing lariat precursor

SP Barrett, PL Wang, J Salzman - elife, 2015 - elifesciences.org
10.7554/eLife.07540.001 Pervasive expression of circular RNA is a recently discovered
feature of eukaryotic gene expression programs, yet its function remains largely unknown. The …

Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome

DT Pride, J Salzman, M Haynes, F Rohwer… - The ISME …, 2012 - academic.oup.com
Viruses are the most abundant known infectious agents on the planet and are significant
drivers of diversity in a variety of ecosystems. Although there have been numerous studies of …