User profiles for Julian Pietsch

Julian MJ Pietsch

- Verified email at synmikro.mpi-marburg.mpg.de - Cited by 162

Julian Pietsch

- Verified email at oncoray.de - Cited by 8

Distributed and dynamic intracellular organization of extracellular information

AA Granados, JMJ Pietsch… - Proceedings of the …, 2018 - National Acad Sciences
Although cells respond specifically to environments, how environmental identity is encoded
intracellularly is not understood. Here, we study this organization of information in budding …

[HTML][HTML] Potential margin reduction in prostate cancer proton therapy with prompt gamma imaging for online treatment verification

S Bertschi, K Stützer, J Berthold, J Pietsch… - Physics and Imaging in …, 2023 - Elsevier
The potential of proton therapy is currently limited due to large safety margins. We estimated
the potential reduction of clinical margins when using prompt gamma imaging (PGI) for …

[HTML][HTML] PyOmeroUpload: A Python toolkit for uploading images and metadata to OMERO

J Hay, E Troup, I Clark, J Pietsch… - Wellcome Open …, 2020 - ncbi.nlm.nih.gov
Tools and software that automate repetitive tasks, such as metadata extraction and deposition
to data repositories, are essential for researchers to share Open Data, routinely. For …

Transition between fermentation and respiration determines history-dependent behavior in fluctuating carbon sources

…, G Perez-Samper, L Vermeersch, JMJ Pietsch… - Elife, 2018 - elifesciences.org
10.7554/eLife.39234.001 Cells constantly adapt to environmental fluctuations. These
physiological changes require time and therefore cause a lag phase during which the cells do not …

[HTML][HTML] Roadmap on biology in time varying environments

…, MJ Rust, C Hepler, J Bass, JMJ Pietsch… - Physical …, 2021 - iopscience.iop.org
Biological organisms experience constantly changing environments, from sudden changes
in physiology brought about by feeding, to the regular rising and setting of the Sun, to …

Determining growth rates from bright-field images of budding cells through identifying overlaps

JMJ Pietsch, AF Muñoz, DYA Adjavon, I Farquhar… - Elife, 2023 - elifesciences.org
Much of biochemical regulation ultimately controls growth rate, particularly in microbes.
Although time-lapse microscopy visualises cells, determining their growth rates is challenging, …

Automatic detection and classification of treatment deviations in proton therapy from realistically simulated prompt gamma imaging data

J Pietsch, C Khamfongkhruea, J Berthold… - Medical …, 2023 - Wiley Online Library
Background A clinical study regarding the potential of range verification in proton therapy (PT)
by prompt gamma imaging (PGI) is carried out at our institution. Manual interpretation of …

Instability of CII is needed for efficient switching between lytic and lysogenic development in bacteriophage 186

IM Murchland, A Ahlgren-Berg, JMJ Pietsch… - Nucleic Acids …, 2020 - academic.oup.com
The CII protein of temperate coliphage 186, like the unrelated CII protein of phage λ, is a
transcriptional activator that primes expression of the CI immunity repressor and is critical for …

A label-free method to track individuals and lineages of budding cells

JMJ Pietsch, AF Muñoz, DYA Adjavon, I Farquhar… - bioRxiv, 2022 - biorxiv.org
Much of biochemical regulation ultimately controls growth rate, particularly in microbes.
Although time-lapse microscopy visualises cells, determining their growth rates is challenging …

[HTML][HTML] Regulation by cyclic di-GMP attenuates dynamics and enhances robustness of bimodal curli gene activation in Escherichia coli

…, K Fritz, I Biazruchka, R Köhler, J Pietsch… - PLoS …, 2023 - journals.plos.org
Curli amyloid fibers are a major constituent of the extracellular biofilm matrix formed by bacteria
of the Enterobacteriaceae family. Within Escherichia coli biofilms, curli gene expression …