Beta2‐adrenergic receptor signaling in CD4+ Foxp3+ regulatory T cells enhances their suppressive function in a PKA‐dependent manner
MG Guereschi, LP Araujo, JT Maricato… - European journal of …, 2013 - Wiley Online Library
… receptor expression in T reg cells or the influence of noradrenaline on their function. Here
we show that F oxp3 + T reg cells express functional B 2 AR . B 2 AR activation in T reg cells …
we show that F oxp3 + T reg cells express functional B 2 AR . B 2 AR activation in T reg cells …
[HTML][HTML] Direct RNA sequencing reveals SARS-CoV-2 m6A sites and possible differential DRACH motif methylation among variants
JHC Campos, JT Maricato, CT Braconi, F Antoneli… - Viruses, 2021 - mdpi.com
The causative agent of COVID-19 pandemic, SARS-CoV-2, has a 29,903 bases positive-sense
single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential …
single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential …
[HTML][HTML] A Recombinant Protein Based on Trypanosoma cruzi P21 Enhances Phagocytosis
…, PCF Dos Santos, FA Martins, D Bahia, JT Maricato… - Plos one, 2012 - journals.plos.org
Background P21 is a secreted protein expressed in all developmental stages of Trypanosoma
cruzi. The aim of this study was to determine the effect of the recombinant protein based …
cruzi. The aim of this study was to determine the effect of the recombinant protein based …
[HTML][HTML] Humoral and cellular responses to vaccination with homologous CoronaVac or ChAdOx1 and heterologous third dose with BNT162b2
…, MM Soane, CT Braconi, JT Maricato… - The Journal of …, 2022 - ncbi.nlm.nih.gov
In a recent systemic literature review, Walsh et al. reported that viral load of severe acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) peaks around symptom onset, and …
respiratory syndrome-coronavirus-2 (SARS-CoV-2) peaks around symptom onset, and …
Anti‐metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10
…, CJM Braga, FV Pereira, JT Maricato… - Immunology and cell …, 2015 - Wiley Online Library
Current therapies against malignant melanoma generally fail to increase survival in most
patients, and immunotherapy is a promising approach as it could reduce the dosage of toxic …
patients, and immunotherapy is a promising approach as it could reduce the dosage of toxic …
The third vaccine dose significantly reduces susceptibility to the B. 1.1. 529 (Omicron) SARS‐CoV‐2 variant
…, A Belmok, BM Ribeiro, JT Maricato… - Journal of Medical …, 2023 - Wiley Online Library
The main coronavirus disease 2019 (COVID‐19) vaccine formulations used today are
mainly based on the wild‐type severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
mainly based on the wild‐type severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
[HTML][HTML] GCN2 kinase plays an important role triggering the remission phase of experimental autoimmune encephalomyelitis (EAE) in mice
Experimental autoimmune encephalomyelitis (EAE) has been widely employed as a model
to study multiple sclerosis (MS) and indeed has allowed some important advances in our …
to study multiple sclerosis (MS) and indeed has allowed some important advances in our …
[HTML][HTML] Epigenetic modulations in activated cells early after HIV-1 infection and their possible functional consequences
JT Maricato, MN Furtado, MC Takenaka, ERM Nunes… - PLoS …, 2015 - journals.plos.org
Epigenetic modifications refer to a number of biological processes which alter the structure
of chromatin and its transcriptional activity such as DNA methylation and histone post-…
of chromatin and its transcriptional activity such as DNA methylation and histone post-…
3D Bioprinted Neural‐Like Tissue as a Platform to Study Neurotropism of Mouse‐Adapted SARS‐CoV‐2
…, RS Diaz, LMR Janini, JT Maricato… - Advanced …, 2022 - Wiley Online Library
The effects of neuroinvasion by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
become clinically relevant due to the numerous neurological symptoms observed in …
become clinically relevant due to the numerous neurological symptoms observed in …
[HTML][HTML] The epitranscriptome of Vero cells infected with SARS-CoV-2 assessed by direct RNA sequencing reveals m6A pattern changes and DRACH motif biases in …
JHC Campos, GV Alves, JT Maricato… - Frontiers in Cellular …, 2022 - frontiersin.org
The epitranscriptomics of the SARS-CoV-2 infected cell reveals its response to viral replication.
Among various types of RNA nucleotide modifications, the m6A is the most common and …
Among various types of RNA nucleotide modifications, the m6A is the most common and …