User profiles for Julien Marlet
 | Julien MarletUniversité de Tours, INSERM U1259 Verified email at univ-tours.fr Cited by 1492 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
…, YL Lau, D Leung, M Coulongeat, J Marlet… - Science …, 2021 - science.org
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
…, D Leung, M Coulongeat, J Marlet… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort
…, JC Plantier, V Thibault, J Marlet… - Proceedings of the …, 2021 - National Acad Sciences
The characterization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral
kinetics in hospitalized patients and its association with mortality is unknown. We analyzed …
kinetics in hospitalized patients and its association with mortality is unknown. We analyzed …
[HTML][HTML] Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to …
We report the strategy leading to the first detection of variant of concern 202012/01 (VOC) in
France (21 December 2020). First, the spike (S) deletion H69–V70 (ΔH69/ΔV70), identified …
France (21 December 2020). First, the spike (S) deletion H69–V70 (ΔH69/ΔV70), identified …
[HTML][HTML] The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism
…, L Plantier, A Lefevre, E Piver, L Bernard, J Marlet… - Scientific reports, 2020 - nature.com
The biological mechanisms involved in SARS-CoV-2 infection are only partially understood.
Thus we explored the plasma metabolome of patients infected with SARS-CoV-2 to search …
Thus we explored the plasma metabolome of patients infected with SARS-CoV-2 to search …
[HTML][HTML] Humoral immunity to SARS-CoV-2 and seasonal coronaviruses in children and adults in north-eastern France
Background Children are underrepresented in the COVID-19 pandemic and often experience
milder disease than adolescents and adults. Reduced severity is possibly due to recent …
milder disease than adolescents and adults. Reduced severity is possibly due to recent …
[HTML][HTML] Antibody responses after a third dose of COVID-19 vaccine in kidney transplant recipients and patients treated for chronic lymphocytic leukemia
The impact of a third dose of COVID-19 vaccine on antibody responses is unclear in
immunocompromised patients. The objective of this retrospective study was to characterize antibody …
immunocompromised patients. The objective of this retrospective study was to characterize antibody …
Influenza vaccination as a novel means of preventing coronary heart disease: Effectiveness in older adults
A Aidoud, J Marlet, D Angoulvant, C Debacq… - Vaccine, 2020 - Elsevier
Atherosclerosis can have various etiologies, including several newly recognized
immunoinflammatory mechanisms. A growing body of evidence suggests that influenza infection is …
immunoinflammatory mechanisms. A growing body of evidence suggests that influenza infection is …
[HTML][HTML] Fatal outcome after reactivation of inherited chromosomally integrated HHV-6A (iciHHV-6A) transmitted through liver transplantation
P Bonnafous, J Marlet, D Bouvet, E Salame… - American Journal of …, 2018 - Elsevier
HHV-6A and HHV-6B are found as inherited and chromosomally integrated forms (iciHHV-6A
and -6B) into all germinal and somatic cells and vertically transmitted in a Mendelian …
and -6B) into all germinal and somatic cells and vertically transmitted in a Mendelian …
[HTML][HTML] Fatal measles inclusion-body encephalitis in adult with untreated AIDS, France
We report a fatal case of measles inclusion-body encephalitis occurring in a woman from
Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen …
Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen …