User profiles for Julien R. C. Bergeron
Julien BergeronKing's College London Verified email at kcl.ac.uk Cited by 1366 |
[HTML][HTML] Structural characterization of SARS-CoV-2: where we are, and where we need to be
…, SLM Lale-Farjat, JRC Bergeron - Frontiers in molecular …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread in humans
in almost every country, causing the disease COVID-19. Since the start of the COVID-19 …
in almost every country, causing the disease COVID-19. Since the start of the COVID-19 …
[HTML][HTML] Cryo-EM of the injectisome and type III secretion systems
JRC Bergeron, TC Marlovits - Current Opinion in Structural Biology, 2022 - Elsevier
Double-membrane-spanning protein complexes, such as the T3SS, had long presented an
intractable challenge for structural biology. As a consequence, until a few years ago, our …
intractable challenge for structural biology. As a consequence, until a few years ago, our …
[PDF][PDF] A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
Interferons (IFNs) induce an antimicrobial state, protecting tissues from infection. Many
viruses inhibit IFN signaling, but whether bacterial pathogens evade IFN responses remains …
viruses inhibit IFN signaling, but whether bacterial pathogens evade IFN responses remains …
[HTML][HTML] A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly
The T3SS injectisome is a syringe-shaped macromolecular assembly found in pathogenic
Gram-negative bacteria that allows for the direct delivery of virulence effectors into host cells. …
Gram-negative bacteria that allows for the direct delivery of virulence effectors into host cells. …
[HTML][HTML] The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex
JRC Bergeron, H Huthoff, DA Veselkov… - PLoS …, 2010 - journals.plos.org
The HIV-1 viral infectivity factor (Vif) protein recruits an E3 ubiquitin ligase complex, comprising
the cellular proteins elongin B and C (EloBC), cullin 5 (Cul5) and RING-box 2 (Rbx2), to …
the cellular proteins elongin B and C (EloBC), cullin 5 (Cul5) and RING-box 2 (Rbx2), to …
Oligomerization requirements for MX2-mediated suppression of HIV-1 infection
…, G Betancor, L Apolonia, JRC Bergeron… - Journal of …, 2016 - Am Soc Microbiol
Human myxovirus resistance 2 (MX2/MXB) is an interferon-stimulated gene (ISG) and was
recently identified as a late postentry suppressor of human immunodeficiency virus type 1 (HIV…
recently identified as a late postentry suppressor of human immunodeficiency virus type 1 (HIV…
[HTML][HTML] Structure and lipid dynamics in the maintenance of lipid asymmetry inner membrane complex of A. baumannii
Multi-resistant bacteria are a major threat in modern medicine. The gram-negative coccobacillus
Acinetobacter baumannii currently leads the WHO list of pathogens in critical need for …
Acinetobacter baumannii currently leads the WHO list of pathogens in critical need for …
[PDF][PDF] The modular structure of the inner-membrane ring component PrgK facilitates assembly of the type III secretion system basal body
The type III secretion system (T3SS) is a large macromolecular assembly found at the surface
of many pathogenic Gram-negative bacteria. Its role is to inject toxic "effector" proteins into …
of many pathogenic Gram-negative bacteria. Its role is to inject toxic "effector" proteins into …
[PDF][PDF] Single-particle cryo-EM analysis of the shell architecture and internal organization of an intact α-carboxysome
Carboxysomes are proteinaceous bacterial microcompartments that sequester the key
enzymes for carbon fixation in cyanobacteria and some proteobacteria. They consist of a virus-…
enzymes for carbon fixation in cyanobacteria and some proteobacteria. They consist of a virus-…
[HTML][HTML] The structure of a type 3 secretion system (T3SS) ruler protein suggests a molecular mechanism for needle length sensing
JRC Bergeron, L Fernández, GA Wasney… - Journal of Biological …, 2016 - ASBMB
The type 3 secretion system (T3SS) and the bacterial flagellum are related pathogenicity-associated
appendages found at the surface of many disease-causing bacteria. These …
appendages found at the surface of many disease-causing bacteria. These …