Glycoprotein B (gB) is one of the essential components for infection by herpes simplex virus-1
(HSV-1). Although several cellular receptors that associate with glycoprotein D (gD), such …

Herpes simplex virus-1 (HSV-1), the prototype of the α-herpesvirus family, causes life-long
infections in humans. Although generally associated with various mucocutaneous diseases, …

Herpes simplex virus 1 (HSV-1) replicates its genome and packages it into capsids within
the nucleus. HSV-1 has evolved a complex mechanism of nuclear egress whereby nascent …

Most patients with coronavirus disease 2019 (COVID-19) experience asymptomatic disease
or mild symptoms, but some have critical symptoms requiring intensive care. It is important …

The AIM2 inflammasome is activated by DNA, leading to caspase-1 activation and release
of pro-inflammatory cytokines interleukin 1β (IL-1β) and IL-18, which are critical mediators in …

The successful entry of herpes simplex virus (HSV) into a cell is a complex process requiring
the interaction of several surface viral glycoproteins with host cell receptors. These viral …

Vesicle-mediated nucleocytoplasmic transport is a nuclear pore-independent mechanism for
the nuclear export of macromolecular complexes, but the molecular basis for this transport …

Importance Although 2 and 3 doses of vaccine have been implemented against the SARS-CoV-2
pandemic, the level of immunity achieved by these additional vaccinations remains …

Herpes simplex virus 1 (HSV-1) enters cells either via fusion of the virion envelope and host
cell plasma membrane or via endocytosis, depending on the cell type. In the study reported …

Herpesviruses have evolved a unique mechanism for nuclear egress of nascent progeny
nucleocapsids: the nucleocapsids bud through the inner nuclear membrane into the …