User profiles for Jung-Jin Lee

Jung Jin Lee

Washington University School of Law
Verified email at wustl.edu
Cited by 300

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

…, K Läll, LA Lange, JJ Lee, B Lehne, H Li… - Nature …, 2018 - nature.com
We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls
of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10 −7 ); of …

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

…, X Guo, A Lamri, M Nakatochi, RA Scott, JJ Lee… - Nature …, 2022 - nature.com
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS)
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…

Maternal and fetal exposure to bisphenol A in Korea

YJ Lee, HY Ryu, HK Kim, CS Min, JH Lee, E Kim… - Reproductive …, 2008 - Elsevier
Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential
risk of human exposure to BPA, little information exists concerning maternal and fetal …

Adaboost for text detection in natural scene

JJ Lee, PH Lee, SW Lee, A Yuille… - … conference on document …, 2011 - ieeexplore.ieee.org
Detecting text regions in natural scenes is an important part of computer vision. We propose
a novel text detection algorithm that extracts six different classes features of text, and uses …

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

…, KD Taylor, YJ Hung, WJ Lee, T Quertermous, IT Lee… - Nature …, 2017 - nature.com
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease
(CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both …

[HTML][HTML] Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments

EL Clarke, LJ Taylor, C Zhao, A Connell, JJ Lee, B Fett… - Microbiome, 2019 - Springer
Background Analysis of mixed microbial communities using metagenomic sequencing
experiments requires multiple preprocessing and analytical steps to interpret the microbial and …

Effect of eriodictyol on glucose uptake and insulin resistance in vitro

…, JJ Lee, Y Kim, IS Kim, JH Han, SG Lee… - Journal of agricultural …, 2012 - ACS Publications
Eriodictyol [2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one] is a flavonoid
with anti-inflammatory and antioxidant activities. Because inflammation and oxidative stress …

[HTML][HTML] The effect of LRRK2 loss-of-function variants in humans

…, JS Ware, AS Havulinna, B Iliadou, JJ Lee… - Nature Medicine, 2020 - nature.com
Human genetic variants predicted to cause loss-of-function of protein-coding genes (pLoF
variants) provide natural in vivo models of human gene inactivation and can be valuable …

Antiplatelet activity of hesperetin, a bioflavonoid, is mainly mediated by inhibition of PLC-γ2 phosphorylation and cyclooxygenase-1 activity

YR Jin, XH Han, YH Zhang, JJ Lee, Y Lim, JH Chung… - Atherosclerosis, 2007 - Elsevier
Diet can be one of the most important factors that influence risks for atherothrombotic diseases.
Hesperetin included in grapefruits and oranges is one candidate that may benefit the …

Live, Attenuated, Tetravalent Butantan–Dengue Vaccine in Children and Adults

…, A Esteves-Jaramillo, T Shekar, JJ Lee… - … England Journal of …, 2024 - Mass Medical Soc
Background Butantan–Dengue Vaccine (Butantan-DV) is an investigational, single-dose, live,
attenuated, tetravalent vaccine against dengue disease, but data on its overall efficacy are …