User profiles for Jussi Kupari

Jussi Kupari

Verified email at ki.se
Cited by 675

[PDF][PDF] An atlas of vagal sensory neurons and their molecular specialization

J Kupari, M Häring, E Agirre, G Castelo-Branco… - Cell reports, 2019 - cell.com
Sensory functions of the vagus nerve are critical for conscious perceptions and for monitoring
visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we present …

[HTML][HTML] Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain

J Kupari, D Usoskin, M Parisien, D Lou, Y Hu… - Nature …, 2021 - nature.com
Distinct types of dorsal root ganglion sensory neurons may have unique contributions to
chronic pain. Identification of primate sensory neuron types is critical for understanding the …

Visceral motor neuron diversity delineates a cellular basis for nipple-and pilo-erection muscle control

…, M Häring, H Abdo, H Hochgerner, J Kupari… - Nature …, 2016 - nature.com
Despite the variety of physiological and target-related functions, little is known regarding the
cellular complexity in the sympathetic ganglion. We explored the heterogeneity of mouse …

[HTML][HTML] Molecular taxonomy of nociceptors and pruriceptors

J Kupari, P Ernfors - Pain, 2023 - journals.lww.com
The ability to feel the warmth of the sun or the coolness of a breeze on a summer’s day; a
pleasant caress of skin; to explore the texture, size, and shape of an object; and to feel pain as …

[PDF][PDF] Dynamic MAPK/ERK activity sustains nephron progenitors through niche regulation and primes precursors for differentiation

A Ihermann-Hella, T Hirashima, J Kupari, K Kurtzeborn… - Stem cell reports, 2018 - cell.com
The in vivo niche and basic cellular properties of nephron progenitors are poorly described.
Here we studied the cellular organization and function of the MAPK/ERK pathway in …

Single-Soma Deep RNA Sequencing of Human Dorsal Root Ganglion Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation

H Yu, D Usoskin, SS Nagi, Y Hu, J Kupari, O Bouchatta… - bioRxiv, 2023 - biorxiv.org
The versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG)
neurons. However, soma transcriptomes of individual human DRG (hDRG) neurons – critical …

Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF

H Li, K Kurtzeborn, J Kupari, Y Gui, E Siefker… - …, 2021 - journals.biologists.com
Nephron endowment, defined during the fetal period, dictates renal and related cardiovascular
health throughout life. We show here that, despite its negative effects on kidney growth, …

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis

…, K Okuyama, J Ungerbäck, J Kupari… - Journal of Experimental …, 2018 - rupress.org
To understand the developmental trajectories in early lymphocyte differentiation, we identified
differentially expressed surface markers on lineage-negative lymphoid progenitors (LPs). …

[HTML][HTML] Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney

…, I Faisal, M Ambrož, X Jin, T Qureshi, J Kupari… - BMC biology, 2022 - Springer
Background MAPK/ERK signaling is a well-known mediator of extracellular stimuli controlling
intracellular responses to growth factors and mechanical cues. The critical requirement of …

Single-soma deep RNA sequencing of human DRG neurons reveals novel molecular and cellular mechanisms underlying somatosensation

H Yu, D Usoskin, S Nagi, Y Hu, J Kupari, O Bouchatta… - 2023 - papers.ssrn.com
The versatility of somatosensation arises from heterogenous human dorsal root ganglion (DRG)
neurons. The critical information to decipher their functions, ie, the soma transcriptome, …