User profiles for Jussi Kupari
Jussi KupariVerified email at ki.se Cited by 675 |
[PDF][PDF] An atlas of vagal sensory neurons and their molecular specialization
Sensory functions of the vagus nerve are critical for conscious perceptions and for monitoring
visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we present …
visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we present …
[HTML][HTML] Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
Distinct types of dorsal root ganglion sensory neurons may have unique contributions to
chronic pain. Identification of primate sensory neuron types is critical for understanding the …
chronic pain. Identification of primate sensory neuron types is critical for understanding the …
Visceral motor neuron diversity delineates a cellular basis for nipple-and pilo-erection muscle control
…, M Häring, H Abdo, H Hochgerner, J Kupari… - Nature …, 2016 - nature.com
Despite the variety of physiological and target-related functions, little is known regarding the
cellular complexity in the sympathetic ganglion. We explored the heterogeneity of mouse …
cellular complexity in the sympathetic ganglion. We explored the heterogeneity of mouse …
[HTML][HTML] Molecular taxonomy of nociceptors and pruriceptors
The ability to feel the warmth of the sun or the coolness of a breeze on a summer’s day; a
pleasant caress of skin; to explore the texture, size, and shape of an object; and to feel pain as …
pleasant caress of skin; to explore the texture, size, and shape of an object; and to feel pain as …
[PDF][PDF] Dynamic MAPK/ERK activity sustains nephron progenitors through niche regulation and primes precursors for differentiation
The in vivo niche and basic cellular properties of nephron progenitors are poorly described.
Here we studied the cellular organization and function of the MAPK/ERK pathway in …
Here we studied the cellular organization and function of the MAPK/ERK pathway in …
Single-Soma Deep RNA Sequencing of Human Dorsal Root Ganglion Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation
The versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG)
neurons. However, soma transcriptomes of individual human DRG (hDRG) neurons – critical …
neurons. However, soma transcriptomes of individual human DRG (hDRG) neurons – critical …
Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF
Nephron endowment, defined during the fetal period, dictates renal and related cardiovascular
health throughout life. We show here that, despite its negative effects on kidney growth, …
health throughout life. We show here that, despite its negative effects on kidney growth, …
Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis
…, K Okuyama, J Ungerbäck, J Kupari… - Journal of Experimental …, 2018 - rupress.org
To understand the developmental trajectories in early lymphocyte differentiation, we identified
differentially expressed surface markers on lineage-negative lymphoid progenitors (LPs). …
differentially expressed surface markers on lineage-negative lymphoid progenitors (LPs). …
[HTML][HTML] Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney
…, I Faisal, M Ambrož, X Jin, T Qureshi, J Kupari… - BMC biology, 2022 - Springer
Background MAPK/ERK signaling is a well-known mediator of extracellular stimuli controlling
intracellular responses to growth factors and mechanical cues. The critical requirement of …
intracellular responses to growth factors and mechanical cues. The critical requirement of …
Single-soma deep RNA sequencing of human DRG neurons reveals novel molecular and cellular mechanisms underlying somatosensation
The versatility of somatosensation arises from heterogenous human dorsal root ganglion (DRG)
neurons. The critical information to decipher their functions, ie, the soma transcriptome, …
neurons. The critical information to decipher their functions, ie, the soma transcriptome, …