Branched-chain amino acids and brain metabolism

JE Sperringer, A Addington, SM Hutson - Neurochemical research, 2017 - Springer
This review aims to provide a historical reference of branched-chain amino acid (BCAA)
metabolism and provide a link between peripheral and central nervous system (CNS) …

Doublecortin-like kinase 1 facilitates dendritic spine growth of pyramidal neurons in mouse prefrontal cortex

KE Murphy, EY Zhang, EV Wyatt, JE Sperringer… - Neuroscience, 2023 - Elsevier
The L1 cell adhesion molecule NrCAM (Neuron-glia related cell adhesion molecule) functions
as a co-receptor for secreted class 3 Semaphorins to prune subpopulations of dendritic …

Ankyrin B promotes developmental spine regulation in the mouse prefrontal cortex

KE Murphy, B Duncan, JE Sperringer, E Zhang… - Cerebral …, 2023 - academic.oup.com
Postnatal regulation of dendritic spine formation and refinement in cortical pyramidal neurons
is critical for excitatory/inhibitory balance in neocortical networks. Recent studies have …

[HTML][HTML] The L1 cell adhesion molecule constrains dendritic spine density in pyramidal neurons of the mouse cerebral cortex

KE Murphy, SD Wade, JE Sperringer… - Frontiers in …, 2023 - frontiersin.org
A novel function for the L1 cell adhesion molecule, which binds the actin adaptor protein
Ankyrin was identified in constraining dendritic spine density on pyramidal neurons in the …

In vitro assays to determine skeletal muscle physiologic function

JE Sperringer, RW Grange - … Regeneration in the Mouse: Methods and …, 2016 - Springer
In vitro muscle contractile function assays are important to characterize the differences between
different muscle types (eg, slow vs. fast), between a diseased and non-diseased muscle, …

The L1 Cell Adhesion Molecule Constrains Dendritic Spine Density through Ankyrin Binding in Pyramidal Neurons of the Mouse Cerebral Cortex

KE Murphy, SD Wade, JE Sperringer, V Mohan… - bioRxiv, 2022 - biorxiv.org
A novel function for L1 cell adhesion molecule and its interaction with Ankyrin, an actin-spectrin
adaptor protein, was identified in constraining dendritic spine density on pyramidal …

[BOOK][B] Post-Translational Modifications of the Paired Box Transcription Factor 7 (Pax7) in Satellite Cells During the Repair of Injured Skeletal Muscle

JE Sperringer - 2014 - search.proquest.com
Satellite cells are normally a quiescent skeletal muscle stem cell pool that upon activation
rapidly proliferate and differentiate to repair damaged muscle fibers. The paired box …

[BOOK][B] Skeletal muscle regeneration in the mouse

M Kyba, Kyba - 2016 - Springer
Although skeletal muscle is the most abundant tissue in the body, playing key roles in
metabolism, heat generation, and macromolecule storage in addition to the obvious role in …

Green tea extract attenuates muscle loss and improves muscle function during disuse, but fails to improve muscle recovery following unloading in aged rats

…, BT Bennett, JC Wilson, J Sperringer… - Journal of applied …, 2015 - journals.physiology.org
In this study we tested the hypothesis that green tea extract (GTE) would improve muscle
recovery after reloading following disuse. Aged (32 mo) Fischer 344 Brown Norway rats were …

[HTML][HTML] Brain–blood amino acid correlates following protein restriction in murine maple syrup urine disease

KR Vogel, E Arning, BL Wasek, S McPherson… - Orphanet journal of rare …, 2014 - Springer
Background Conventional therapy for patients with maple syrup urine disease (MSUD) entails
restriction of protein intake to maintain acceptable levels of the branched chain amino acid…