We present a biochemical model of the wall shear stress-induced activation of endothelial
nitric oxide synthase (eNOS) in an endothelial cell. The model includes three key …

Recent advances in electron microscopy have enabled the imaging of single cells in 3D at
nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to …

Advances in imaging methods such as electron microscopy, tomography, and other modalities
are enabling high-resolution reconstructions of cellular and organelle geometries. Such …

Recent advances in microscopy and 3D reconstruction methods have allowed for characterization
of cellular morphology in unprecedented detail, including the irregular geometries of …

Recent advances in electron microscopy have, for the first time, enabled imaging of single
cells in 3D at a nanometer length scale resolution. An uncharted frontier for in silico biology is …

It is well known that many cells adapt their geometry in response to their environment, and
these changes in geometry can influence their function significantly. For years, the difficulty of …

Cell shape and function have been shown to be closely related. This is particularly true in
the case of synapses, where dynamic changes to dendritic spine size and shape are …

Calcium ions are key signaling molecules in dendritic spines, the small neurotransmitter-receiving
protrusions along dendrites. Their dynamics have been shown to regulate many …

To date, the practice of global emergency medicine (GEM) has involved being “on the
ground” supporting in‐country training of local learners, conducting research, and providing …

The Second Workshop on Extreme Precision Radial Velocities defined circa 2015 the state
of the art Doppler precision and identified the critical path challenges for reaching 10 cm s− 1 …