It is widely accepted that obesity and associated metabolic diseases, including type 2
diabetes, are intimately linked to diet. However, the gut microbiota has also become a focus for …

Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and …

The gut is home to trillions of microorganisms that have fundamental roles in many aspects
of human biology, including immune function and metabolism 1 , 2 . The reduced diversity of …

The distal human intestine represents an anaerobic bioreactor programmed with an enormous
population of bacteria, dominated by relatively few divisions that are highly diverse at the …

Germ-free mice were maintained on polysaccharide-rich or simple-sugar diets and colonized
for 10 days with an organism also found in human guts, Bacteroides thetaiotaomicron, …

BACKGROUND The collection of trillions of microbes inhabiting the human gut, called the
microbiome or microbiota, has captivated the biomedical research community for the past …

The human intestine, colonized by a dense community of resident microbes, is a frequent
target of bacterial pathogens. Undisturbed, this intestinal microbiota provides protection from …

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI)
disorders. Determining its mechanistic role in disease has been difficult due to apparent …

Gut microbiota alterations have been described in several diseases with altered gastrointestinal
(GI) motility, and awareness is increasing regarding the role of the gut microbiome in …

We have created a compendium of single cell transcriptomic data from the model organism
Mus musculus comprising more than 100,000 cells from 20 organs and tissues. These data …