User profiles for Jyoti Iyer
 | Jyoti IyerThe University of Tulsa Verified email at utulsa.edu Cited by 294 |
CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.
…, M Bergwell, E Smith, D Mathew, J Iyer - JoVE (Journal of Visualized …, 2020 - jove.com
The bacterial Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/Streptococcus
pyogenes CRISPR-associated protein (Cas) system has been harnessed by …
pyogenes CRISPR-associated protein (Cas) system has been harnessed by …
What's Nu (SAP) in mitosis and cancer?
Unperturbed mitosis is a prerequisite for the generation of two genetically identical daughter
cells. Nucleolar-spindle associated protein (NuSAP) is an important mitotic regulator. The …
cells. Nucleolar-spindle associated protein (NuSAP) is an important mitotic regulator. The …
A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex
J Iyer, MY Tsai - Cellular signalling, 2012 - Elsevier
Aurora B kinase forms the enzymatic core of the Chromosomal Passenger Complex (CPC)
and is a master regulator of mitosis. Understanding the regulation of Aurora B is critical to …
and is a master regulator of mitosis. Understanding the regulation of Aurora B is critical to …
[HTML][HTML] KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis
L Zhang, J Iyer, A Chowdhury, M Ji, L Xiao… - Journal of Biological …, 2012 - ASBMB
The Hippo pathway controls organ size and tumorigenesis by inhibiting cell proliferation
and promoting apoptosis. KIBRA was recently identified as a novel regulator of the Hippo …
and promoting apoptosis. KIBRA was recently identified as a novel regulator of the Hippo …
Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A
Here we provide evidence in support of an inherent role for Arpc1b, a component of the Arp2/3
complex, in regulation of mitosis and demonstrate that its depletion inhibits Aurora A …
complex, in regulation of mitosis and demonstrate that its depletion inhibits Aurora A …
A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication, dendrite morphogenesis, and ciliogenesis in Caenorhabditis elegans
The human SASS6(I62T) missense mutation has been linked with the incidence of primary
microcephaly in a Pakistani family, although the mechanisms by which this mutation causes …
microcephaly in a Pakistani family, although the mechanisms by which this mutation causes …
[HTML][HTML] Protein phosphatase 1 down regulates ZYG-1 levels to limit centriole duplication
N Peel, J Iyer, A Naik, MP Dougherty, M Decker… - PLoS …, 2017 - journals.plos.org
In humans perturbations of centriole number are associated with tumorigenesis and
microcephaly, therefore appropriate regulation of centriole duplication is critical. The C. elegans …
microcephaly, therefore appropriate regulation of centriole duplication is critical. The C. elegans …
The retromer complex regulates C. elegans development and mammalian ciliogenesis
…, A Davis, D Mathew, N Naslavsky, J Iyer… - Journal of cell …, 2022 - journals.biologists.com
The mammalian retromer consists of subunits VPS26 (either VPS26A or VPS26B), VPS29
and VPS35, and a loosely associated sorting nexin (SNX) heterodimer or a variety of other …
and VPS35, and a loosely associated sorting nexin (SNX) heterodimer or a variety of other …
Using Microinjection to Generate Genetically Modified Caenorhabditis elegans by CRISPR/Cas9 Editing
In this chapter, we describe the procedure for generating genetically modified Caenorhabditis
elegans using microinjection via the Cas9-mediated Clustered Regularly Interspaced …
elegans using microinjection via the Cas9-mediated Clustered Regularly Interspaced …
[HTML][HTML] Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model
MK Townsend, NJ Carr, JG Iyer, SM Horne, PS Gibbs… - BMC microbiology, 2008 - Springer
Background The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the
expression levels of non-flagellar genes, including 21 genes that are involved in central …
expression levels of non-flagellar genes, including 21 genes that are involved in central …