Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit
KA Doiron, TC Hoffmann… - Cochrane Database of …, 2018 - cochranelibrary.com
… Two researchers (KAD, and a research assistant) independently used the data collection
form shown in our protocol (Doiron 2013), to extract data from all included studies. We resolved …
form shown in our protocol (Doiron 2013), to extract data from all included studies. We resolved …
Protean careers at work: Self-direction and values orientation in psychological success
How do self-direction and personal values influence career outcomes? Such questions
have been central in research on the protean career—a career process characterized by the …
have been central in research on the protean career—a career process characterized by the …
[HTML][HTML] Theranostic cells: emerging clinical applications of synthetic biology
Synthetic biology seeks to redesign biological systems to perform novel functions in a
predictable manner. Recent advances in bacterial and mammalian cell engineering include the …
predictable manner. Recent advances in bacterial and mammalian cell engineering include the …
[PDF][PDF] Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
J Dupaul-Chicoine, G Yeretssian, K Doiron… - Immunity, 2010 - cell.com
Inflammatory caspases are essential effectors of inflammation and cell death. Here, we
investigated their roles in colitis and colorectal cancer and report a bimodal regulation of …
investigated their roles in colitis and colorectal cancer and report a bimodal regulation of …
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease
…, EJ Rivera, SJ Soscia, K Doiron… - Journal of …, 2006 - content.iospress.com
The cascade of Alzheimer's disease (AD) neurodegeneration is associated with persistent
oxidative stress, mitochondrial dysfunction, impaired energy metabolism, and activation of pro-…
oxidative stress, mitochondrial dysfunction, impaired energy metabolism, and activation of pro-…
[PDF][PDF] Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2
Cellular inhibitor of apoptosis proteins (cIAPs) block apoptosis, but their physiological
functions are still under investigation. Here, we report that cIAP1 and cIAP2 are E3 ubiquitin …
functions are still under investigation. Here, we report that cIAP1 and cIAP2 are E3 ubiquitin …
[HTML][HTML] The Caspase-1 Digestome Identifies the Glycolysis Pathway as a Target during Infection and Septic Shock*♦
Caspase-1 is an essential effector of inflammation, pyroptosis, and septic shock. Few caspase-1
substrates have been identified to date, and these substrates do not account for its wide …
substrates have been identified to date, and these substrates do not account for its wide …
[PDF][PDF] Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
Pathogen and danger recognition by the inflammasome activates inflammatory caspases
that mediate inflammation and cell death. The cellular inhibitor of apoptosis proteins (cIAPs) …
that mediate inflammation and cell death. The cellular inhibitor of apoptosis proteins (cIAPs) …
Physiotherapy for cystic fibrosis in Australia and New Zealand: a clinical practice guideline
…, R Black, S Bowen, R Day, J Depiazzi, K Doiron… - …, 2016 - Wiley Online Library
Physiotherapy management is a key element of care for people with cystic fibrosis (CF)
throughout the lifespan. Although considerable evidence exists to support physiotherapy …
throughout the lifespan. Although considerable evidence exists to support physiotherapy …
[HTML][HTML] Heat-induced protein structure and subfractions in relation to protein degradation kinetics and intestinal availability in dairy cattle
K Doiron, P Yu, JJ McKinnon, DA Christensen - Journal of Dairy Science, 2009 - Elsevier
The objectives of this study were to reveal protein structures of feed tissues affected by heat
processing at a cellular level, using the synchrotron-based Fourier transform infrared …
processing at a cellular level, using the synchrotron-based Fourier transform infrared …