A photoactivable natural product with broad antiviral activity against enveloped viruses, including highly pathogenic coronaviruses
…, S Bordage, M Bamba, K Hervouet… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has
highlighted the need for broad-spectrum antivirals against coronaviruses (CoVs). Here, …
highlighted the need for broad-spectrum antivirals against coronaviruses (CoVs). Here, …
[HTML][HTML] Processing and subcellular localization of the hepatitis E virus replicase: identification of candidate viral factories
K Metzger, C Bentaleb, K Hervouet… - Frontiers in …, 2022 - frontiersin.org
Hepatitis E virus (HEV) is the major cause of acute hepatitis worldwide. HEV is a positive-sense
RNA virus expressing three open reading frames (ORFs). ORF1 encodes the ORF1 non–…
RNA virus expressing three open reading frames (ORFs). ORF1 encodes the ORF1 non–…
[HTML][HTML] The endocytic recycling compartment serves as a viral factory for hepatitis E virus
C Bentaleb, K Hervouet, C Montpellier… - Cellular and Molecular …, 2022 - Springer
Although hepatitis E virus (HEV) is the major leading cause of enterically transmitted viral
hepatitis worldwide, many gaps remain in the understanding of the HEV lifecycle. Notably, viral …
hepatitis worldwide, many gaps remain in the understanding of the HEV lifecycle. Notably, viral …
[HTML][HTML] An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell
K Hervouet, M Ferrié, M Ankavay, C Montpellier… - PLoS …, 2022 - journals.plos.org
Hepatitis E virus (HEV) infection is the most common cause of acute viral hepatitis worldwide.
Hepatitis E is usually asymptomatic and self-limiting but it can become chronic in …
Hepatitis E is usually asymptomatic and self-limiting but it can become chronic in …
The fate of Hepatitis E virus capsid protein is regulated by an Arginine-Rich Motif
K Hervouet, M Ferrié, M Ankavay, C Montpellier… - 2021 - hal.science
Producing multifunctional proteins is one of the major strategies developed by viruses to
condense their genetic information. Here, we investigated the molecular determinants of the …
condense their genetic information. Here, we investigated the molecular determinants of the …
Etude des mécanismes d'adressage et de maturation de la protéine de capside ORF2 du virus de l'hépatite E.
K Hervouet - 2022 - theses.fr
Le virus de l'hépatite E (HEV) est l'agent étiologique le plus fréquent d'hépatite aiguë dans
le monde. Le nombre de cas d'hépatite E par an est estimé à 20 millions et est responsable …
le monde. Le nombre de cas d'hépatite E par an est estimé à 20 millions et est responsable …
Characterization of the hepatitis E virus replicase
K Metzger, C Bentaleb, K Hervouet, V Alexandre… - bioRxiv, 2021 - biorxiv.org
Hepatitis E virus (HEV) is the major cause of acute hepatitis worldwide. HEV is a positive-sense
RNA virus expressing 3 open reading frames (ORFs). ORF1 encodes the ORF1 non– …
RNA virus expressing 3 open reading frames (ORFs). ORF1 encodes the ORF1 non– …
Étude de l'interaction entre les peroxysomes et le virus de l'hépatite C
EM de Fourchambault - 2023 - theses.hal.science
L'hépatite C est une maladie chronique occasionnant une atteinte hépatique évolutive
pouvant conduire en 20 ou 30 ans à l'apparition d'une cirrhose ou d'un hépatocarcinome. L'agent …
pouvant conduire en 20 ou 30 ans à l'apparition d'une cirrhose ou d'un hépatocarcinome. L'agent …
[HTML][HTML] Defects in cellular sorting and retroviral assembly induced by GGA overexpression
Background We previously demonstrated that overexpression of Golgi-localized, γ-ear
containing, Arf-binding (GGA) proteins inhibits retrovirus assembly and release by disrupting the …
containing, Arf-binding (GGA) proteins inhibits retrovirus assembly and release by disrupting the …
[HTML][HTML] Generation of fluorescent HCV pseudoparticles to study early viral entry events-involvement of Rab1a in HCV entry
C Bhattacharjee, A Mukhopadhyay - VirusDisease, 2022 - Springer
Understanding the early events in viral biology holds the key to the development of potent
preventives. In this study, fluorescent hepatitis C virus pseudoparticles (HCVpp) have been …
preventives. In this study, fluorescent hepatitis C virus pseudoparticles (HCVpp) have been …